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Ramipril
go.drugbank.com/drugs/DB00178ApprovedInvestigationalRamiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). … Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys.
Mixtures: RAMIPRIL COMP HEU 5/25MG N, DELMUNO 5/5 MGCategories: Heterocyclic Compounds, 2-Ring, Agents Acting on the Renin-Angiotensin SystemMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigational[A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527] … [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.
Mixtures: METOPROLOL HCT S 100/12.5, METOPROLOL HCT S 100/12.5Categories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AntagonistsLeiomyosarcoma
go.drugbank.com/conditions/DBCOND0002821Drugs: SorafenibSynonyms: Leiomyosarcoma, no subtype, Leiomyomosarcoma, no subtype (morphologic abnormality)Light mineral oil
go.drugbank.com/drugs/DB11579ApprovedMixtures: Ti Lub Lotion, QV FLARE UP BATH OILSynonyms: Drakeol 5Indapamide
go.drugbank.com/drugs/DB00808ApprovedInvestigational[A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. … [A204155] Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension and continue to grow in popularity, falling behind only ACE inhibitors in terms of prescription
Mixtures: COVERATRIX 5 MG/1.25 MG/10 MG COMPRIMIDOS RECUBIERTOS CON PELÍCULA, COVERATRIX 10 MG / 2.5 MG / 5 MG COMPRIMIDOS RECUBIERTOS CON PELÍCULACategories: Non Potassium Sparing Diuretics, Cytochrome P-450 SubstratesCarboxyamidotriazole
go.drugbank.com/drugs/DB11960InvestigationalCarboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: CAIDL-alpha-Tocopherol
go.drugbank.com/drugs/DB14476ApprovedInvestigationalMixtures: L-SOLUVIT N, VITALIPID® N - ADULTCategories: Vitamin EThymoma
go.drugbank.com/conditions/DBCOND0001482Drugs: IfosfamideSynonyms: Thymoma, no ICD-O subtype, Thymoma, no International Classification of Diseases for Oncology subtypeDiltiazem
go.drugbank.com/drugs/DB00343ApprovedInvestigationalApproved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. … It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle during depolarization.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: (+)-cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ester, (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetateClonidine
go.drugbank.com/drugs/DB00575ApprovedInvestigationalClonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.[A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD. … [L7237,L54536,L7240,L7243,L7246] Clonidine was granted FDA approval on 3 September 1974.[L7237]
Categories: Sympathomimetics in Glaucoma Therapy, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 2,6-Dichloro-N-2-imidazolidinylidenebenzenamine, 2-((2,6-Dichlorophenyl)imino)imidazolidine