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Displaying results 591 - 600 of 10000 in total
  1. Drug

    Hepatitis B immune globulin

    go.drugbank.com/drugs/DB05276
    ApprovedInvestigational

    Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. … HBIG is prepared from the plasma of donors who have high antibody levels of the hepatitis B surface antigen. It is extracted from the Cohn fraction II.

    Products: Igantibe 200 IU/ml, HEPATECT CP 500 IU 10 ML FLAKON
  2. Drug

    Captopril

    go.drugbank.com/drugs/DB01197
    ApprovedInvestigational

    ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension. … Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).

    Mixtures: CAPTOPRIL HCT AL 50/25Categories: Agents Acting on the Renin-Angiotensin System
  3. Drug

    Agomelatine

    go.drugbank.com/drugs/DB06594
    ApprovedInvestigational

    Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. … The Committee for Medical Products for Human Use (CHMP) recommended refusal of marketing authorization on 27 July 2006. The major concern was that efficacy had not been sufficiently shown.

    Products: AGOMELATIN AL 25MG FTA
  4. Drug

    Terbutaline

    go.drugbank.com/drugs/DB00871
    ApprovedInvestigational

    [A230328] It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.[L32088]

    Products: TERBUTALIN AL 2.5, TERBUTALIN AL RETARD
  5. Drug

    Finasteride

    go.drugbank.com/drugs/DB01216
    ApprovedInvestigational

    Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone … [A178159] In the treatment of benign prostate hyperplasia, alpha-blockers such as [tamsulosin] and [terazosin] are also used.

    Products: Ag-finasteride, Sandoz Finasteride A
  6. Drug

    Hydromorphone

    go.drugbank.com/drugs/DB00327
    ApprovedIllicitInvestigational

    Due to these modifications, it presents a very high potency and comparable side effect profile to the parent compound. … Structurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8.

    Categories: Heterocyclic Compounds with 4 or More Rings, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: HYDROMORPHON AL 4MG RET, HYDROMORPHON AL 8MG RET
  7. Drug

    Ramosetron

    go.drugbank.com/drugs/DB09290
    Investigational

    It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondansetron. … Ramosetron is a _serotonin 5-HT3 receptor antagonist_ commonly employed to treat nausea and vomiting, in addition to certain diarrheal conditions.

    Products: NASEA OD
  8. Drug

    Oxazepam

    go.drugbank.com/drugs/DB00842
    Approved

    Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and anxiety disorders. … [A203516] It is an active metabolite of both [diazepam] and [temazepam][A39486] and undergoes very little biotransformation following absorption, making it unlikely to participate in pharmacokinetic interactions

    International brands: Ox-PamProducts: OXAZEPAM AL 10
  9. Drug

    Caffeine

    go.drugbank.com/drugs/DB00201
    ApprovedInvestigational

    Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. … [T716] Caffeine is also used in a variety of cosmetic products and can be administered topically, orally, by inhalation, or by injection.

    Mixtures: Nu-acetaco #1, Ru-21 Hangover ReliefCategories: combinations of xanthines
  10. Drug

    Phenol

    go.drugbank.com/drugs/DB03255
    ApprovedInvestigational

    Phenol is also used as an oral analgesic or anesthetic in products such as Chloraseptic to treat pharyngitis. … Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores.

    Mixtures: Au Kah Chuen Skin Lotion, Absorbine Jr Pro No Mess Roll-on PlusCategories: Compounds used in a research, industrial, or household setting