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Suprofen
go.drugbank.com/drugs/DB00870ApprovedWithdrawnIt inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Amfecloral
go.drugbank.com/drugs/DB08924ExperimentalFor a short period of time, it was available under the brand Acutran and indicated as an appetite suppressant, but this product no longer exists. … It acts as a prodrug which splits to form amphetamine and chloral hydrate, similarly to clobenzorex and related compounds, except that the N-substituent, in this case, yields a compound that is active
Lonapegsomatropin
go.drugbank.com/drugs/DB16220ApprovedInvestigational[A237605,L36380,L36405] Unlike somatropin, which requires daily dosing, lonapegsomatropin can be administered as a single weekly dose. … Lonapegsomatropin, also known as TransCon hGH or ACP 001, is a methoxypegylated prodrug of human growth hormone ([somatropin]) indicated for the treatment of children 1 year and older, weighing at least
Terlipressin
go.drugbank.com/drugs/DB02638ApprovedInvestigational[L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions with diminished vasomotor tone. … Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor.[A2601] It is a prodrug of [lypressin], or lysine vasopressin.
Avacincaptad pegol
go.drugbank.com/drugs/DB15165ApprovedInvestigational[A260801] Avacincaptag pegol was approved by the FDA on August 4, 2023, under the brand name IZERVAY for the treatment of GA secondary to AMD.
Amlexanox
go.drugbank.com/drugs/DB01025ApprovedWithdrawnAmlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers.
Etrasimod
go.drugbank.com/drugs/DB14766ApprovedInvestigational[A261831] Etrasimod was approved on October 13, 2023, by the FDA under the brand name VELSIPITY for the treatment of adults with moderately to severely active ulcerative colitis.
Hypochlorite
go.drugbank.com/drugs/DB11123ApprovedInvestigationalHypochlorite is often used as a chemical reagent for chlorination and oxidation reactions.
Lanolin
go.drugbank.com/drugs/DB11112ApprovedLanolin is used as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and facial cosmetics. … It is used as an emollient, cosmetic, and pharmaceutic aid [L2580].
Levomefolic acid
go.drugbank.com/drugs/DB11256ApprovedLevomefolate is approved as a food additive and is designated a GRAS (generally regarded as safe) compound [L773]. … It is available commercially as a crystalline form of the calcium salt (Metafolin(R)), which has the stability required for use as a supplement [A19276].