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INM005
go.drugbank.com/drugs/DB16499InvestigationalIt was studied for pharmacokinetics, efficacy, and safety in a completed trial (NCT04494984). … Additionally, a retrospective cohort study investigated the effectiveness and safety of specific hyperimmune equine serum for severe hospitalized COVID-19 patients (NCT04954235)
Synonyms: INM-005 (PURIFIED FAB'2 FRACTION OF EQUINE HYPERIMMUNE SERUM GENERATED FROM ANTIGENIC STIMULATION WITH THE SARS-COV2 RBD PROTEIN)Calcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalD<sub>3</sub>. … Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin
Categories: Vitamin D and Analogues, Cytochrome P-450 SubstratesSynonyms: 1-alpha-25-Dihydroxyvitamin D3, 1α,25-dihydroxyvitamin D3Rifaximin
go.drugbank.com/drugs/DB01220ApprovedInvestigationalsyndrome (IBS-D) in adult women and men. … Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered
Categories: Heterocyclic Compounds with 4 or More Rings, Cytochrome P-450 SubstratesSynonyms: Rifamycin L 105, Rifamycin L 105SVFluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalFluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. … Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP2B6 InducersProducts: Fluvastatin Sandoz 40 mg - Hartkapseln, Fluvastatin Sandoz 20 mg - HartkapselnUrea
go.drugbank.com/drugs/DB03904ApprovedInvestigationalA compound formed in the liver from ammonia produced by the deamination of amino acids.
Mixtures: ROZA %1 + %2 KREM (30 G), UREACORT %0,5 + %5 KREM (30 G)Products: EXCİPİAL HYDRO % 2 EMÜLSİYON, 200 ML, EXCİPİAL LİPO % 4 EMÜLSİYON, 200 MLKetotifen
go.drugbank.com/drugs/DB00920ApprovedInvestigationalIt has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and [azatadine]. … Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell stabilizing properties.
Categories: Heterocyclic Compounds, 1-RingProducts: ZADITEN SRO FILM TABLET 2 MG, 30 ADET, ZADITEN ORAL DAMLA 1 MG/ML, 25 MLAmlitelimab
go.drugbank.com/drugs/DB18835Investigationaland Older With Moderate-to-severe Atopic Dermatitis (COAST 2)). … Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years
Synonyms: Immunoglobulin g4 (235-proline,242-glutamic acid), anti-(human ox40 ligand) (human monoclonal ky1005-2d10 .gamma.4-chain), disulfide with human monoclonal ky1005-2d10 .kappa.-chain, dimerCarteolol
go.drugbank.com/drugs/DB00521ApprovedA beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: CARTEOL LP %2 UZUN ETKILI GOZ DAMLASI, 3 ML, CARTEOL LP %1 UZUN ETKILI GOZ DAMLASI, 3 MLChelerythrine
go.drugbank.com/drugs/DB17024ExperimentalA benzophenanthridine alkaloid evaluated as a kinase-inhibitor.[A252982]
Categories: Heterocyclic Compounds, 3-Ring, Heterocyclic Compounds with 4 or More RingsSynonyms: 1,2-dimethoxy-12-methyl(1,3)dioxolo)4',5':4,5)benzo(1,2-c)phenanthridinium, (1,3)benzodioxolo(5,6-c)phenanthridinium, 1,2-dimethoxy-12-methyl-Tretinoin
go.drugbank.com/drugs/DB00755ApprovedInvestigationalNutraceutical[A257689] In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. … Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin A] (retinol).
Synonyms: Tretin M, (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acidInternational brands: Stieva-A