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Displaying results 611 - 620 of 1803 in total
  1. Target

    Copper-transporting ATPase 2

    go.drugbank.com/bio_entities/BE0003664
    TransporterHumans

    Copper ion transmembrane transporter involved in the export of copper out of the cells. … It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload

    Polypeptides: Copper-transporting ATPase 2Synonyms: Copper pump 2
  2. Target

    CMV DNA Terminase Complex

    go.drugbank.com/bio_entities/BE0010221
    TargetHuman Cytomegalovirus

    Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. … Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.

  3. Drug

    Zanubrutinib

    go.drugbank.com/drugs/DB15035
    ApprovedInvestigational

    Zanubrutinib is a novel Bruton's tyrosine kinase (BTK) inhibitor used for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. … [L39367] In September 2021, zanubrutinib was granted another accelerated approval for the treatment of relapsed or refractory marginal zone lymphoma who have received at least one anti-CD20-based regimen

  4. Indication

    Primary Immune Complex Mediated Membranoproliferative Glomerulonephritis

    go.drugbank.com/conditions/DBCOND0173486
    Drugs: Pegcetacoplan
    Synonyms: Primary Immune Complex Mediated Membranoproliferative Glomerulonephritis
  5. Target

    Diamine oxidase [copper-containing]

    go.drugbank.com/bio_entities/BE0004667
    EnzymePig

    Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed:1457410, PubMed:8144586). Its preferred substrates in vitro are the diamines hi...

    Polypeptides: Diamine oxidase [copper-containing]Synonyms: Amine oxidase copper domain-containing protein 1, Amiloride-sensitive amine oxidase [copper-containing]
  6. Drug

    20-Hydroxyecdysone

    go.drugbank.com/drugs/DB16935
    Investigational

    Synonyms: Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2.beta.,3.beta.,5.beta.,22r)-
  7. Drug

    Azenosertib

    go.drugbank.com/drugs/DB18028
    Investigational

    Synonyms: 3h-pyrazolo(3,4-d)pyrimidin-3-one, 1-((7r)-7-ethyl-6,7-dihydro-7-hydroxy-5h-cyclopenta(b)pyridin-2-yl)-1,2-dihydro-6-((4-(4-methyl-1-piperazinyl)phenyl)amino)-2-(2-propen-1-yl)-
  8. Drug

    TP-1287

    go.drugbank.com/drugs/DB18104
    Investigational

    Synonyms: 4h-1-benzopyran-4-one, 2-(2-chlorophenyl)-5-hydroxy-8-((3s,4r)-3-hydroxy-1-methyl-4-piperidinyl)-7-(phosphonooxy)-
  9. Drug

    Potassium

    go.drugbank.com/drugs/DB14500
    ApprovedInvestigational

    [A186928] Many conditions and diseases interfere with normal body potassium balance, and underconsumption of potassium is one example.

    Mixtures: One A Day Tab, Swiss One
  10. Drug

    Indacaterol

    go.drugbank.com/drugs/DB05039
    ApprovedInvestigational

    Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease.