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Tizanidine
go.drugbank.com/drugs/DB00697ApprovedInvestigationalTizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury [T574]. … Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition.
Mixtures: ALERTADINA® A TABLETAS RECUBIERTASCategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexParecoxib
go.drugbank.com/drugs/DB08439ApprovedInvestigationalA letter of non-approval for parecoxib was issued by the FDA in 2005. … Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union.
Products: PARECOXB parecoxib (as sodium) 40mg powder for solution for injectionClozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigational[L905] Due to its severe adverse effects profile, clozapine is only available through a restricted program under a Risk Evaluation Mitigation Strategy (REMS) called the Clozapine REMS Program.[L905] … Despite its effectiveness in treating both positive and negative symptoms of schizophrenia, clozapine was briefly removed from the market in various jurisdictions in 1970 due to severe agranulocytosis.
Categories: Dopamine D2 Receptor AntagonistsProducts: Aa-clozapineSpironolactone
go.drugbank.com/drugs/DB00421ApprovedInvestigationalSpironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. … [L44602] Off-label uses of spironolactone include hirsutism, female pattern hair loss, and adult acne vulgaris.
Mixtures: SPIRO D TABLINEN 100MGProducts: ALDACTONE A, SPIRONOLACTON AL 50Fluorescein
go.drugbank.com/drugs/DB00693ApprovedInvestigationalA phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal
Synonyms: D&C Yellow No. 7, D and C Yellow No. 7Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of ChemicalsAzithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalAzithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl … group at the 9a position on the aglycone ring, which allows for the prevention of its metabolism.
Products: Azithromycin Dr. Friedrich Eberth 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, Ag-azithromycinIcatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigationalIt is resistant to bradykinin-cleaving enzyme degradation and has a potency of 2-3 times higher than earlier B<sub>2</sub> receptors antagonists, thus representing a new class of medication. … [A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema.
Products: ICATIBANT DR. REDDY'SHydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigational[L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect. … Hydroxyzine is a first-generation histamine H<sub>1</sub>-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.
Products: Nu-hydroxyzine, AA PHARMA HYDROXYZINE CAPSULE 10 mgFluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalFluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. … Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.
Products: FLUVASTATIN AL 80MG RETARDBisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigational[A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such … [A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs.
Mixtures: CORBIS® D, CONCOR AMProducts: Nu-bisoprolol, Ag-bisoprolol