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AV-COVID-19
go.drugbank.com/drugs/DB15802InvestigationalThe monocytes are then differentiated in vitro into dendritic cells with IL-4 and GM-CSF, incubated with SARS-CoV-2 antigens prior to administration. … As of July 2020, the company is pursuing an adaptive Phase IB-II Randomized Clinical Trial (NCT04386252) to test the vaccine.
Levonadifloxacin
go.drugbank.com/drugs/DB16219InvestigationalLevonadifloxacin is under investigation in clinical trial NCT03405064 (Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections
Melarsomine
go.drugbank.com/drugs/DB11528ExperimentalVet approvedIt is the only FDA-approved treatment for adult heartworm infection in dogs, however, is is not approved for use in dogs with late-stage infection. … Melarsomine is a trypanocidal agent marketed by Merial under the trade name Immiticide.
Chlormadinone acetate
go.drugbank.com/drugs/DB15903ApprovedWithdrawnChlormadinone acetate is a progesterone derivative first synthesized in 1961. … However, the use of these drugs was associated with the development of mammary tumors in dogs. In 1972, the FDA withdrew its approval for the use of chlormadinone acetate in all products.
Cortisone
go.drugbank.com/drugs/DB14681InvestigationalIt has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. … It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
Gambir
go.drugbank.com/drugs/DB14298InvestigationalGambir is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Pomegranate
go.drugbank.com/drugs/DB14317InvestigationalPomegranate is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mesoheme
go.drugbank.com/drugs/DB02577ExperimentalIt is found free in tissues and as the prosthetic group in many hemeproteins.
Preimplantation factor
go.drugbank.com/drugs/DB16301InvestigationalPreimplantation factor is under investigation in clinical trial NCT03593460 (Phase II Autoimmune Hepatitis).
D-Tyrosine
go.drugbank.com/drugs/DB03839ExperimentalIn animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.