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Nicardipine
go.drugbank.com/drugs/DB00622ApprovedInvestigationalIt has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. … It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Cardene Cap 30mg, Cardene IVBiotin
go.drugbank.com/drugs/DB00121ApprovedInvestigationalNutraceuticalA water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Mixtures: Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA, Super Daily No 2Categories: Vitamin B Complex, Heterocyclic Compounds, 1-RingNystatin
go.drugbank.com/drugs/DB00646ApprovedInvestigationalVet approved[L10686] It is one of the most effective antifungal agents synthesized by bacteria, in this case a strain of _Streptomyces noursei_,[L10776] and is closely related to [amphotericin B], differing only slightly … [A188562] Nystatin has a greater antifungal activity than amphotericin B - parenterally administered nystatin, however, is associated with significant toxicity and is not available in a formulation appropriate
Mixtures: METRONIDAZOL / NISTATINA 500MG/100.000 UI, OVAZOL CON NISTATINA OVULOSCategories: Compounds used in a research, industrial, or household settingGlyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigationalGlyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. … [L8123] It is typically given to patients who cannot be managed with the standard first line therapy, [metformin].
Mixtures: MELLIMET G ® TABLETAS RECUBIERTAS CON PELÍCULA 500MG + 2.5 MG, SIL-NORBORAL ® 5/500 MGCategories: Drugs Used in Diabetes, P-glycoprotein inhibitorsD-glucose
go.drugbank.com/drugs/DB01914ApprovedInvestigationalVet approved[A19399] It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. … [L786] Glucose is listed on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.
Synonyms: D-Glucose in linear form, D-glucoseSalts: D-glucose monohydrateGanciclovir
go.drugbank.com/drugs/DB01004ApprovedInvestigationalAn acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Categories: MATE 1 Substrates, MATE 2 SubstratesSynonyms: 2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-oneSelegiline
go.drugbank.com/drugs/DB01037ApprovedInvestigationalVet approvedA selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability.
Synonyms: L-DeprenalinCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Compounds used in a research, industrial, or household settingFluorouracil
go.drugbank.com/drugs/DB00544ApprovedInvestigationalA pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Mixtures: Actikerall 5 mg/g + 100 mg/g Lösung zur Anwendung auf der Haut, VERRUTOL %0,5 + %10 DERİ ÇÖZELTİSİ (15 G)Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic IndexPostmenopausal Osteoporoses
go.drugbank.com/conditions/DBCOND0110643Drugs: EthinylestradiolSynonyms: Type I osteoporosisEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigationalAs the binding of esomeprazole to the (H+, K+)-ATPase enzyme is irreversible and new enzyme needs to be expressed in order to resume acid secretion, esomeprazole's duration of antisecretory effect persists … Esomeprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme
Mixtures: RUMONAL® PRO 15, RUMONAL® PRO 7.5Categories: Antiinflammatory and Antirheumatic Products, Non-Steroids, Cytochrome P-450 Substrates