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AVR-RD-05
go.drugbank.com/drugs/DB18631ExperimentalAVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme.
Synonyms: Ex vivo, lentiviral vector (LV)-mediated, genetically modified autologous cell therapy intended for the stable provision of functional human iduronate-2-sulfatase (IDS) enzyme to subjects with Hunter syndromeDocusate
go.drugbank.com/drugs/DB11089ApprovedInvestigationalStill docusate is available in over-the-counter products as a common laxative. … Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation[A32201].
Mixtures: Sennosides 8.6 Mg and Docusate Sodium 50 Mg Tablets, Senna Plus Standardized Senna Concentrate 8.6 mg and Docusate Sodium 50 mg EachProducts: M-docusate Sodium 100 mg, M-docusate CalciumGadoversetamide
go.drugbank.com/drugs/DB00538ApprovedGadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.
Categories: Compounds used in a research, industrial, or household settingProducts: CIPROFLOXACINA 100 MG / 10 ML, OPTIMARK 500 MIKROMOL/ML IV. ENJ. ICIN COZELTI ICEREN KUL.HAZIR SIRINGA, 30 MLZopapogene imadenovec
go.drugbank.com/drugs/DB24672ApprovedInvestigational[L54081] Zopapogene imadenovec is a non-replicating adenoviral vector–based immunotherapy that expresses a fusion antigen from selected regions of HPV-6/11 proteins to elicit an immune response in RRP. … Recurrent respiratory papillomatosis (RRP) is a rare, debilitating disease driven by chronic human papillomavirus (HPV) 6 or 11 infection and characterized by recurrent benign tumors in the respiratory
Synonyms: under control of a human cytomegalovirus (CMV) promoter and terminated with a 3' untranslated region and a simian virus 40 (SV40) polyadenylation signal, DNA (recombinant replication-deficient Gorilla gorilla gorilla adenovirus strain GC4 vector PRGN-2012 human cytomegalovirus promoter plus human papillomavirus 6/11 E2, E4, E6, E7 protein 11 epitope-containingSodium oxybate
go.drugbank.com/drugs/DB09072ApprovedInvestigational[A18723] For safety reasons, sodium oxybate is a controlled substance only available through a restricted program in approved countries. … [L30598] It is a sodium salt of [gamma-Hydroxybutyric acid], an endogenous cerebral inhibitory neurotransmitter [A251445] and a metabolite of the inhibitory neurotransmitter GABA.
Products: Natriumoxybat Kalceks 500 mg/ml Lösung zum Einnehmen, Natriumoxybat neuraxpharm 500 mg/ml Lösung zum EinnehmenGonadorelin
go.drugbank.com/drugs/DB00644ApprovedInvestigationalVet approvedIt is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary.
Products: LH-RH FERRING 0,1 MG/ML IV ENJEKSIYONLUK COZELTI ICEREN AMPUL, 1 ADET, Kryptocur 0,2 mg/0,1 ml - nasale SprühlösungNofazinlimab
go.drugbank.com/drugs/DB18852InvestigationalNofazinlimab is under investigation in clinical trial NCT04194775 (A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma).
Synonyms: Immunoglobulin g4 (223-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal cs1003 .gamma.4-chain), disulfide with human-mus musculus monoclonal cs1003 .kappa., Recombinant pd-1 mab cs1003Citalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigationalIt is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. … [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: M-citalopram, CITOL 20 MG FILM KAPLI TABLET, 30 ADETOlopatadine
go.drugbank.com/drugs/DB00768ApprovedIt is a structural analog of [doxepin], which has a minimal anti-allergic activity. … Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions.
Mixtures: OFNOL FRESH % 0.1 + %0.15 STERİL OFTALMİK ÇÖZELTİ, 1 ADETCategories: Heterocyclic Compounds, 3-Ring, Cytochrome P-450 SubstratesPeanut
go.drugbank.com/drugs/DB10553ApprovedPeanut allergenic extract is used in allergenic testing.
Mixtures: PALFORZIA (Level 3), PALFORZIA (Level 3)Products: PALFORZIA (Level 2), PALFORZIA (Level 4)