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Mexiletine
go.drugbank.com/drugs/DB00379ApprovedInvestigationalAntiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Synonyms: 1-(2',6'-dimethylphenoxy)-2-aminopropane, (±)-1-(2,6-dimethylphenoxy)propan-2-amineCategories: Antiarrhythmics, Class I, Cytochrome P-450 SubstratesProcyclidine
go.drugbank.com/drugs/DB00387ApprovedInvestigationalA muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-yl-propan-1-ol hydrochloride, 1-Cyclohexyl-1-phenyl-3-pyrrolidino-1-propanolDigoxin
go.drugbank.com/drugs/DB00390ApprovedInvestigational[A178225] It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. … [A178234] Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein inducersInternational brands: Digocard-GNisoldipine
go.drugbank.com/drugs/DB00401ApprovedNisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: isobutyl methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylateRemoxipride
go.drugbank.com/drugs/DB00409ApprovedWithdrawnRemoxipride is an atypical antipsychotic agent that is specific for dopamine D<sub>2</sub> receptors.
Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 SubstratesAmpicillin
go.drugbank.com/drugs/DB00415ApprovedInvestigationalVet approvedAmpicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Mixtures: DEVASİD 1 G/0,5 G I.M. ENJEKSİYONLUK TOZ, 1 FLAKON, DUOBAK 2 G/1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADETCategories: Penicillin G, Heterocyclic Compounds, 2-RingFamciclovir
go.drugbank.com/drugs/DB00426ApprovedInvestigationalFamciclovir is a prodrug of penciclovir with higher oral bioavailability. … Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles).
Categories: Heterocyclic Compounds, 2-RingSynonyms: 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine, 2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetateCyproheptadine
go.drugbank.com/drugs/DB00434ApprovedInvestigationalCyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsSynonyms: 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine, 4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidineEntecavir
go.drugbank.com/drugs/DB00442ApprovedInvestigationalEntecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine … Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS).
Categories: Hepatitis B virus, Cytochrome P-450 SubstratesProducts: KALVIR® 1 MG, Tecavir 1 (Entecavir Tablets 1 mg)Epirubicin
go.drugbank.com/drugs/DB00445ApprovedInvestigationalAn anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Categories: UGT2B7 Substrates with a Narrow Therapeutic IndexSynonyms: (1S,3S)-3-GLYCOLOYL-1,2,3,4,6,11-HEXAHYDRO-3,5,12-TRIHYDROXY-10-METHOXY-6,11-DIOXO-1-NAPHTHACENYL 3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-ARABINO-HEXOPYRANOSIDE, 4'-Epiadriamycin