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Displaying results 6381 - 6390 of 10000 in total

Drug
R-30490
go.drugbank.com/drugs/DB09179
Experimental
R-30490 is an opioid related to carfentanil used as an animal tranquilizer. … It was first synthesized by Janssen Pharmaceutica as part of a structure-activity relationship study of fentanly and its derivatives.
Categories: Heterocyclic Compounds, 1-Ring
Drug
Daledalin
go.drugbank.com/drugs/DB09189
Experimental
Daledin (UK-3557-15) is a selective norepinephrine reuptake inhibitor. It has no effects on the reuptake of serotonin or dopamine, and no antihistamine or anticholinergic properties.
Categories: Heterocyclic Compounds, 2-Ring
Drug
Tandamine
go.drugbank.com/drugs/DB09192
Experimental
Tandamine is an analog of pirandamine and it acts as a selective serotonin reuptake inhibitor (SSRI).
Categories: Heterocyclic Compounds, 2-Ring
Drug
CP-39,332
go.drugbank.com/drugs/DB09193
Experimental
CP-39,332 is a serotonin-norepinephrine reuptake inhibitor (SNRI). … It is part of a group of monoamine reuptake inhibitor stereoisomers including tametraline (1R,4S-), CP-24,442 (1S,4R-), CP-22,185 (cis-), and CP-22,186 that show varying efficiency.
Drug
Lorpiprazole
go.drugbank.com/drugs/DB09195
Approved
Lorpiprazole is a serotonin antagonist and reuptake inhibitor used for the treatment of major depressive disorder.[A31634] It is a piperazinyl-triazole derivative.[T83]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
Drug
Netoglitazone
go.drugbank.com/drugs/DB09199
Experimental
Netoglitazone (MCC-555) is a hypoglycemic agent.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inhibitors
Drug
Cirazoline
go.drugbank.com/drugs/DB09202
Experimental
Cirazoline acts on a number of α adrenergic receptors. It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2.
Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-1 Receptor Agonists
Drug
Synephrine
go.drugbank.com/drugs/DB09203
Investigational
The similarity of naming between m-synephrine and the unsubstituted form, synephrine, is a source of some confusion however m-synephrine refers to a related drug more commonly known as phenylephrine. … It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine.
Synonyms: p-synephrine
Drug
Arotinolol
go.drugbank.com/drugs/DB09204
Investigational
It is a thiopropanolamine with a tertiary butyl moiety. It has been studied for its potential to be an antihypertensive therapy.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
Drug
Pegloticase
go.drugbank.com/drugs/DB09208
ApprovedInvestigational
[L42425] Pegloticase has a longer terminal elimination half-life thanks to the addition of a polyethylene glycol (PEG) group. … [A249980] The PEG group also gives pegloticase a lower potential to induce an immune response.
Categories: Compounds used in a research, industrial, or household setting