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Displaying results 631 - 640 of 10000 in total
  1. Drug

    Ocrelizumab

    go.drugbank.com/drugs/DB11988
    ApprovedInvestigational

    Primary progressive multiple sclerosis (PPMS) accounts for 10-15% of the overall population of patients with MS, and leads to the gradual worsening of neurologic disability from symptom onset, often without … [A31739] Compared to non-humanized CD20 antibodies such as [rituximab], ocrelizumab is expected to be less immunogenic with repeated infusions, improving the benefit-to-risk profile for patients with MS

    Products: OCREVUS 300 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 2 ADET, OCREVUS 300 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET
  2. Drug

    Anakinra

    go.drugbank.com/drugs/DB00026
    ApprovedInvestigational

    [A247000] Anakinra is produced using the _E. Coli_ bacterial expression system. On November 14, 2001, it was approved by the FDA for the treatment of rheumatoid arthritis. … It was later approved for the treatment of NOMID and DIRA on December 21, 2012, and December 18, 2020, respectively.

    Products: Kıneret 100 mg/ 0.67 ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör, 7 ADET, Kıneret 100 mg/ 0.67 ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör, 28 ADET
  3. Drug

    Sebelipase alfa

    go.drugbank.com/drugs/DB11563
    ApprovedInvestigational

    It was first approved by both the FDA and EMA in 2015 and is marketed under the brand name Kanuma (Alexion Pharmaceuticals).[L39337,L39342]

    Synonyms: SBC-102Products: KANUMA® 2 MG/ML CONCENTRADO PARA SOLUCION PARA INFUSION.
  4. Drug

    Ferric ammonium citrate

    go.drugbank.com/drugs/DB09501
    ApprovedWithdrawn

    Products: FOLITON 250 MG/5 ML ŞURUP, 120 ML, KİNAMALT SİROP, 250 G
  5. Drug

    Adenosine

    go.drugbank.com/drugs/DB00640
    ApprovedInvestigational

    [A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole]

    Mixtures: A.H.c Cotton 100 Mask Skin Ceramide, A.H.c Cotton 100 Mask Multi PeptideProducts: Mizon Hyaluronic Acid 100, ADENOSIN-L.M. 5 MG/ML ENJ/INF. ICIN COZ. ICEREN 10 ML 10 FLAKON
  6. Drug

    Venetoclax

    go.drugbank.com/drugs/DB11581
    ApprovedInvestigational

    Venetoclax is approximately 10 times more potent than navitoclax with regard to induction of apoptosis in CLL cells [A40022]. … A new indication was approved in 2018 for the treatment patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), with or without 17p deletion, who have received at least one

    Synonyms: 4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro-2H-pyran-4-ylmethyl)amino)phenyl)sulfonyl)-2-(1H-pyrrolo(2,3-b)pyridin-5-yloxy)benzamide, 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamideProducts: VENCLYXTO 100 MG FILM KAPLI TABLET, 7 ADET, VENCLYXTO 100 MG FILM KAPLI TABLET, 14 ADET
  7. Drug

    Acitretin

    go.drugbank.com/drugs/DB00459
    ApprovedInvestigational

    It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.

    Synonyms: (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acidProducts: NEOTIGASON 10 MG KAPSUL, 100 ADET, PSÖRETİN 10 MG SERT KAPSÜL ,100 ADET
  8. Drug

    Zonisamide

    go.drugbank.com/drugs/DB00909
    ApprovedInvestigational

    In 1989, it was approved for commercial use in Japan. The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] … [L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors

    Products: ZALIPIN 100 MG KAPSÜL ,100 KAPSÜL, EPİZONYA 100 MG KAPSÜL, 100 ADET
  9. Drug

    Prednisone

    go.drugbank.com/drugs/DB00635
    ApprovedInvestigationalVet approved

    [A187463] It is biologically inert and converted to [prednisolone] in the liver.[L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496]

    Products: Rectodelt 100 mg Zäpfchen, PredniSONE Tablets, USP, 20 mg
  10. Drug

    Diphenhydramine

    go.drugbank.com/drugs/DB01075
    ApprovedInvestigational

    However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. … Diphenhydramine has also been shown to be implicated in a number of neurotransmitter systems that affect behaviour including dopamine, norepinephrine, serotonin, acetylcholine, and opioid [A1539].

    Mixtures: Ibuprofen 200 mg and Diphenhydramine Citrate 38 mg, TANOL 100 ML LOSYONCategories: Antihistamines, Anesthetics, Etc.