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Desirudin
go.drugbank.com/drugs/DB11095ApprovedWithdrawnIt has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. … It is mainly indicated for the prevention of deep vein thrombosis in hip replacement surgery patients.
Phosmet
go.drugbank.com/drugs/DB11448ExperimentalVet approvedIt is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals, and vines to control aphids, suckers, mites, and fruit flies.
Categories: Compounds used in a research, industrial, or household settingLinsitinib
go.drugbank.com/drugs/DB06075InvestigationalAn orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. … IGF-1R inhibitor OSI-906 selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis.
Nitrocefin
go.drugbank.com/drugs/DB11592ExperimentalNitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance.
Categories: Compounds used in a research, industrial, or household settingNP-50301
go.drugbank.com/drugs/DB05662ExperimentalThe majority of sufferers of DES are postmenopausal women; and clinical research around the world has suggested the benefits of both topical and systemic estrogen therapy in the treatment of DES in this … It is estimated that about 30% of postmenopausal women suffer symptoms of DES, which accounts for over 12 million women in the U.S.
Rolitetracycline
go.drugbank.com/drugs/DB01301ApprovedWithdrawnA pyrrolidinylmethyl tetracycline.
Synonyms: N-(Pyrrolidinomethyl)tetracycline, N-(1-Pyrrolidinylmethyl)-tetracyclineIrsogladine
go.drugbank.com/drugs/DB13056InvestigationalIrsogladine is under investigation in clinical trial NCT02581696 (The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult Volunteers).
Categories: Compounds used in a research, industrial, or household settingSparfloxacin
go.drugbank.com/drugs/DB01208ApprovedWithdrawnDNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.
LC16M8
go.drugbank.com/drugs/DB05019InvestigationalIt is the only attenuated vaccine to be licensed for use in humans to prevent smallpox infection.
Berberine
go.drugbank.com/drugs/DB04115ApprovedInvestigationalWithdrawnAn alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants.