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Tubocurarine
go.drugbank.com/drugs/DB01199ApprovedWithdrawn[A216008] Tubocurarine is a benzylisoquinoline derivative and shares this structural backbone with a number of plant-derived alkaloids, including [morphine] and [papaverine]. … Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid.
Synonyms: d-tubocurarine, 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraraniumCategories: Heterocyclic Compounds, 2-RingSparfloxacin
go.drugbank.com/drugs/DB01208ApprovedWithdrawnSparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase.
Synonyms: cis-5-Amino-1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acidCategories: 4-Quinolones, P-glycoprotein substratesCeftriaxone
go.drugbank.com/drugs/DB01212ApprovedInvestigationalCeftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. … [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges[A215582], eyes[A215647], and inner ear[A215627].
Mixtures: RENIBIT®, SEFABEL 1 G I.M. ENJEKSIYONLUK ÇÖZELTI HAZIRLAMAK IÇIN KURU TOZ IÇEREN FLAKON ,1 ADETCategories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-RingMetipranolol
go.drugbank.com/drugs/DB01214ApprovedWithdrawnA beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.
Synonyms: Acetic acid 4-(2-hydroxy-3-isopropylamino-propoxy)-2,3,6-trimethyl-phenyl esterCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesMivacurium
go.drugbank.com/drugs/DB01226ApprovedWithdrawnMivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. … It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.
Categories: Heterocyclic Compounds, 2-RingProducts: MİVACRON 10 MG/5 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, MIVACRON INJECTION 10 mg/5 mlDiphenidol
go.drugbank.com/drugs/DB01231ApprovedWithdrawnDiphenidol is an antiemetic agent used in the treatment of vomiting and vertigo. Diphenidol overdose may result in serious toxicity in children.
Synonyms: Diphenyl(3-(1-piperidyl)propyl)carbinol, alpha,alpha-Diphenyl-1-piperidinebutanolCategories: Heterocyclic Compounds, 1-RingMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalDiabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. … [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GERD).
Synonyms: 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamideMixtures: CLIFAR® GOTAS, PLASIL®ENZIMATICOLevodopa
go.drugbank.com/drugs/DB01235ApprovedInvestigationalThe first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product called Sinemet that was approved on May 2, 1975[A177781,L6133]. … Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label].
Synonyms: 3-Hydroxy-L-tyrosine, (−)-3-(3,4-dihydroxyphenyl)-L-alanineMixtures: CARBIDOPA X 25 MG Y LEVODOPA X 250 MG, CARBIDOPA X 25 MG Y LEVODOPA X 250 MGBromodiphenhydramine
go.drugbank.com/drugs/DB01237ApprovedBromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies. Ethanolamine antihistamines produce marked sedation in most patients.
Synonyms: 2-(p-bromo-α-phenylbenzyloxy)-N,N-dimethylethylamine, β-(p-bromobenzhydryloxy)ethyldimethylamineDecamethonium
go.drugbank.com/drugs/DB01245ApprovedIt is a short acting depolarizing muscle relaxant. It is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor.
Synonyms: N,N,N,N',N',N'-hexamethyl-1,10-decanediaminium