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Psilocybin
go.drugbank.com/drugs/DB11664InvestigationalPsilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
Amperozide
go.drugbank.com/drugs/DB08927ExperimentalAlternatively, amperozide's main use lies in veterinary medicine, where it is typically employed to minimize aggression and stress in intensively farmed pigs. … Amperozide is a diphenylbutylpiperazine atypical antipsychotic which antagonizes 5-HT2A receptors. It inhibits dopamine release and alters the firing of dopaminergic neurons.
Nalorphine
go.drugbank.com/drugs/DB11490ExperimentalVet approvedIt is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence. … It acts at two opioid receptors—at the mu receptor it has antagonistic effects, and at the kappa receptors it exerts high-efficacy agonistic characteristics.
Loprazolam
go.drugbank.com/drugs/DB13643ExperimentalIt is a positive modulator of GABA-A receptor that enhances the inhibitory neurotransmission. It is not an FDA-approved drug. … It is indicated for the short-term treatment of insomnia including difficulty in falling asleep and/or frequent nocturnal awakenings.
Alphacetylmethadol
go.drugbank.com/drugs/DB01555ExperimentalIllicitIt is used mainly in the treatment of narcotic dependence. [PubChem]
Nicotinyl alcohol
go.drugbank.com/drugs/DB04145ExperimentalIt is used in vasospasm and threatened gangrene. [PubChem]
ChulaCov19 mRNA vaccine
go.drugbank.com/drugs/DB16445ExperimentalThe next phase of this study is for phase I and II clinical trials (NCT04566276) beginning in January 2021. … The ChulaCov19 vaccine is mRNA-based and was developed in Thailand’s Chulalongkorn University in collaboration with the University of Pennsylvania in the US[L30673, L30678].
Cefovecin
go.drugbank.com/drugs/DB11505ExperimentalVet approvedIt is used for the treatment of skin infections caused by Pasturella multocida in cats, and Staphylococcus intermedius/S. canis in dogs. … Cefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs.
OM85
go.drugbank.com/drugs/DB16533InvestigationalOM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity.
Equilin
go.drugbank.com/drugs/DB02187ExperimentalIt has a total of four double bonds in the A- and B-ring. High concentration of equilin is found in the urine of pregnant mares.
Synonyms: 1,3,5,7-Estratetraen-3-ol-17-one