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Displaying results 651 - 660 of 10000 in total
  1. Drug

    Mycophenolate mofetil

    go.drugbank.com/drugs/DB00688
    ApprovedInvestigational

    [L7363] It is marketed by Roche Pharmaceuticals and was granted FDA approval for the prophylaxis of transplant rejection in 1995. … [A180799,A180805] Previously, mycophenolic acid (MPA) was administered to individuals with autoimmune diseases beginning in the 1970s, but was discontinued due to gastrointestinal effects and concerns

    Categories: Mycophenolic Acid and ProdrugsProducts: MYFENAX 250MG, CELLCEPT 250MG
  2. Drug

    Trolamine salicylate

    go.drugbank.com/drugs/DB11079
    Approved

    Trolamine salicylate serves as an active ingredient in topical over-the-counter products for temporary management of mild to moderate muscular and joint pains. … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid.

    Mixtures: Arthritis Extra Strength Roll-ON LotionProducts: Up and Up Pain Relief Odorless, Up and Up Odor-free Pain Relieving Cream
  3. Drug

    Acarbose

    go.drugbank.com/drugs/DB00284
    ApprovedInvestigational

    [L31633,A37868] By inhibiting the activity of these enzymes, acarbose limits the absorption of dietary carbohydrates and the subsequent postprandial increase in blood glucose and insulin levels. … Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines.

    Categories: Drugs Used in Diabetes, metformin and acarboseProducts: GLUCOBAY TABLET 100MG, Gacose Tablet 100mg
  4. Drug

    Sarilumab

    go.drugbank.com/drugs/DB11767
    ApprovedInvestigational

    [A27262] Sarilumab was developed by Sanofi and Regeneron Pharmaceuticals, Inc; it was US FDA-approved in May 2017 and followed by EU approval in June 2017 for the treatment of moderate to severe rheumatoid … [A27265] RA is a chronic inflammatory disease characterized by polyarthritis, and its treatment has been challenged by the different responses in every patient.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: KEVZARA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 150MG, KEVZARA Solution for Injection in Pre-filled Pen 150mg
  5. Drug

    Abiraterone

    go.drugbank.com/drugs/DB05812
    ApprovedInvestigational

    [L54773,L54768] As abiraterone has poor oral bioavailability and is susceptible to hydrolysis by esterases, abiraterone acetate was developed as an orally bioavailable prodrug with enhanced stability … Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis

    Categories: niraparib and abiraterone, abiraterone and corticosteroidsProducts: XBIRA® 500MG, ZYTIGA FILM-COATED TABLET 500MG
  6. Drug

    Lavender oil

    go.drugbank.com/drugs/DB14566
    Approved

    Products: Bux Guard
  7. Drug

    Flubendazole

    go.drugbank.com/drugs/DB08974
    ApprovedInvestigationalWithdrawn

    Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.

    Categories: Antiparasitic Products, Insecticides and RepellentsProducts: FLUBENFAR 500MG TABLETA, FLUVERMAL SUSPENSION 20MG/ML
  8. Drug

    Tocilizumab

    go.drugbank.com/drugs/DB06273
    ApprovedInvestigational

    [L40164] Subsequently, it was granted approval by Health Canada and the FDA in October [L43697] and December 2022, respectively. … Two biosimilar versions of tocilizumab have since been approved by the FDA: tocilizumab-bavi, in September 2023,[L48385] and Tyenne® (tocilizumab), in June 2024.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: Actemra Concentrate for Solution for Infusion 20mg/ml, ACTEMRA (162 MG SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE)
  9. Drug

    Prochlorperazine

    go.drugbank.com/drugs/DB00433
    ApprovedInvestigationalVet approved

    [L6637] Prochlorperazine was first developed in the 1950s [L6643] and was first approved by the FDA in 1956. … [label] It mainly works by depressing the chemoreceptor trigger zone and blocking D2 dopamine receptors in the brain. It was shown to also block histaminergic, cholinergic and noradrenergic receptors.

    Synonyms: Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine, N-(gamma-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazineProducts: PMS Prochlorperazine Inj 5mg/ml, Prochlorperazine Mesylate Inj 5mg/ml
  10. Drug

    Doxycycline

    go.drugbank.com/drugs/DB00254
    ApprovedInvestigationalVet approved

    [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730] … Doxycycline is a broad-spectrum antibiotic synthetically derived from [oxytetracycline].[L42880] It is a second-generation tetracycline that was first discovered in 1967.

    Categories: Alimentary Tract and Metabolism, Antiinfectives and Antiseptics for Local Oral TreatmentProducts: Doryx 100mg Cap, Doxycin Cap 100mg