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Ibuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigational[A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. … [A39076] On the available products, ibuprofen is administered as a racemic mixture.
Mixtures: MULTIDOL® NOCHE, NORAVER®G FAST TOTAL NOCHE.Categories: Topical Products for Joint and Muscular Pain, Experimental Unapproved Treatments for COVID-19Mometasone
go.drugbank.com/drugs/DB00764ApprovedInvestigationalMometasone is a corticosteroid not currently used in medical products. [Mometasone furoate] however, is still in use.
Categories: Corticosteroids for inhalation use, Drugs for Obstructive Airway DiseasesProducts: MOMETASONE EGNintedanib
go.drugbank.com/drugs/DB09079ApprovedInvestigational[L8453,L8459] It was first approved for use in the United States in 2014. … [A185237] As a chemotherapeutic agent for NSCLC, nintedanib, in combination with [Docetaxel], is reserved for patients who have tried and failed first-line chemotherapeutic options.[L8459]
Products: NINTEDANIB EGNicotine
go.drugbank.com/drugs/DB00184ApprovedInvestigationalNicotine is also important medically because of its presence in tobacco smoke.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Drugs Used in Addictive DisordersSynonyms: L(−)-nicotine, 3-(N-methylpyrollidino)pyridineTioconazole
go.drugbank.com/drugs/DB01007ApprovedTioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". … Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane.
Mixtures: GYNOMAX L VAJINAL OVUL, 7 ADETCategories: Antifungals for Topical Use, Antifungals for Dermatological UseTrospium
go.drugbank.com/drugs/DB00209ApprovedInvestigationalTrospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably. … [L6208] An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination.
Categories: Drugs for Urinary Frequency and Incontinence, Drugs for Functional Gastrointestinal DisordersProducts: Trospium Chloride ERMagnesium hydroxide
go.drugbank.com/drugs/DB09104ApprovedInvestigationalMagnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. … It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers).
Mixtures: Eno, EnoCategories: Drugs for Acid Related DisordersColchicine
go.drugbank.com/drugs/DB01394ApprovedInvestigationalColchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum autumnale_, or "autumn crocus."[A183611] Its use was first approved by the FDA in 1961. … [L47591] It has also been investigated in other inflammatory and fibrotic conditions.[A183602]
Categories: Experimental Unapproved Treatments for COVID-19, Preparations With No Effect on Uric Acid MetabolismProducts: L-CISIN, PMS-colchicine ERFluorouracil
go.drugbank.com/drugs/DB00544ApprovedInvestigationalA pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic IndexProducts: 5-FLUOROURACIL 1000 MG/20 ML ENJ. COZ. ICIN FLAKON, 5-FLUOROURACIL EBEWE 500 MG/10 ML ENJ. ICIN COZ. ICEREN FLAKONTrolamine salicylate
go.drugbank.com/drugs/DB11079ApprovedTrolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. … Trolamine salicylate serves as an active ingredient in topical over-the-counter products for temporary management of mild to moderate muscular and joint pains.
Mixtures: Arthritis Extra Strength Roll-ON LotionProducts: Dr Joe lab ARTHRITIS EXTRA STRENGTH, Antiphlogistine Rub A-535 No Odour Fmla Ont