Search
Eluxadoline
go.drugbank.com/drugs/DB09272ApprovedInvestigationalEluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). … The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central nervous system and peripherally in the gastrointestinal system.
Categories: mu-Opioid Receptor Agonist, Heterocyclic Compounds, 1-RingSynonyms: 5-({(4-carbamoyl-2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2-methoxybenzoic acidThymidine monophosphate
go.drugbank.com/drugs/DB01643Investigational5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-deoxy-5-methyluridine 5'-(dihydrogen phosphate), 5'-TMPUridine monophosphate
go.drugbank.com/drugs/DB03685Investigational5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 5'-uridylic acid, Uridine 5'-monophosphateFlurocitabine
go.drugbank.com/drugs/DB20317ExperimentalFlurocitabine is a small molecule drug. … Flurocitabine has a monoisotopic molecular weight of 243.07 Da.
Synonyms: 5-fluorocyclocytidine, 5'-fluorocyclocytidineAprobarbital
go.drugbank.com/drugs/DB01352ExperimentalIllicitA primary treatment indicated for the use of aprobarbital was subsequently insomnia. … Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSynonyms: 5-allyl-5-isopropylpyrimidine-2,4,6(1H,3H,5H)-trione, 5-(1-methylethyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrioneFluorometholone
go.drugbank.com/drugs/DB00324ApprovedInvestigationalA glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders.
Mixtures: EFEMOLINE 5 ML DAMLA, FLU-SURE T® SUSPENSIÓN OFTÁLMICACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersCephalexin
go.drugbank.com/drugs/DB00567ApprovedInvestigationalVet approved[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. … [A179071] Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,L6547] Cephalexin was approved by the FDA on 4 January 1971.
Synonyms: (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acidInternational brands: L-KeflexCaspofungin
go.drugbank.com/drugs/DB00520ApprovedInvestigationalIt shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall. … Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSynonyms: (4R,5S)-5-((2-Aminoethyl)amino)-N(sup 2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans, -3-hydroxy-L-proline cyclic (6-1)-peptideTelbivudine
go.drugbank.com/drugs/DB01265ApprovedWithdrawnTelbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus.
Categories: Heterocyclic Compounds, 1-Ring, Hepatitis B Virus Nucleoside Analog Reverse Transcriptase InhibitorSynonyms: 1-(2-deoxy-β-L-ribofuranosyl)-5-methyluracil, β-L-2'-deoxythymidine(5-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-1,2-dideoxy-ribofuranose-5-monophosphate
go.drugbank.com/drugs/DB04060ExperimentalSynonyms: (5-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-1,2-dideoxy-ribofuranose-5-monophosphate