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Displaying results 651 - 660 of 1186 in total
  1. Target

    G protein-coupled receptor 55

    go.drugbank.com/bio_entities/BE0005802
    TargetHumans

    G protein-coupled receptor that binds to several ligands including 2-arachidonoyl lysophosphatidylinositol or lysophosphatidylglucoside with high affinity, leading to rapid and transient activation of

    Polypeptides: G protein-coupled receptor 55Function: cannabinoid receptor activity
  2. Target

    Tyrosine-protein kinase receptor UFO

    go.drugbank.com/bio_entities/BE0009412
    TargetHumans

    Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell

    Polypeptides: Tyrosine-protein kinase receptor UFO
  3. Target

    Ephrin type-A receptor 4

    go.drugbank.com/bio_entities/BE0009438
    TargetHumans

    Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. … The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.

    Polypeptides: Ephrin type-A receptor 4Synonyms: Tyrosine-protein kinase receptor SEK
  4. Target

    Ephrin type-B receptor 6

    go.drugbank.com/bio_entities/BE0009442
    TargetHumans

    Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. … Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (PubMed:12517763, PubMed:15955811).

    Polypeptides: Ephrin type-B receptor 6Synonyms: Tyrosine-protein kinase-defective receptor EPH-6
  5. Target

    Interleukin-1 receptor type 2

    go.drugbank.com/bio_entities/BE0009549
    TargetHumans

    Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1.

    Polypeptides: Interleukin-1 receptor type 2Synonyms: IL-1 type II receptor, Interleukin-1 receptor beta
  6. Target

    Outer membrane ferric siderophore receptor

    go.drugbank.com/bio_entities/BE0009807
    TransporterPseudomonas aeruginosa (strain UCBPP-PA14)

    Polypeptides: Outer membrane ferric siderophore receptorSynonyms: Putative outer membrane ferric siderophore receptor
  7. Target

    Neuronal Acetylcholine (nACh) Receptor Subunits

    go.drugbank.com/bio_entities/BE0009927
    TargetHumans

    Modulates receptor assembly and increases receptor sensitivity to nicotine when associated with CHRNB2, CHRNA4 and/or CHRNA6 as well as CHRNA3 and CHRNB4 (PubMed:11118490, PubMed:16835356). … CHRNA3:CHRNB4 being predominant in neurons of the autonomic ganglia, it is known as ganglionic nicotinic receptor (PubMed:31488329).

    Polypeptides: Neuronal acetylcholine receptor subunit alpha-10, Neuronal acetylcholine receptor subunit alpha-2Synonyms: Nicotinic acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor subunit alpha-2
  8. Target

    Free fatty acid receptor 3

    go.drugbank.com/bio_entities/BE0010132
    TargetHumans

    That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins. … G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis

    Polypeptides: Free fatty acid receptor 3Synonyms: G protein-coupled receptor 41
  9. Target

    Vascular endothelial growth factor receptor

    go.drugbank.com/bio_entities/BE0010227
    TargetHumans

    Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. … Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival

    Polypeptides: Vascular endothelial growth factor receptor 1, Vascular endothelial growth factor receptor 2Synonyms: Kinase insert domain receptor, Tyrosine-protein kinase receptor FLT
  10. Target

    Cytokine receptor-like factor 2

    go.drugbank.com/bio_entities/BE0010586
    TargetHumans

    Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5.

    Polypeptides: Cytokine receptor-like factor 2Synonyms: TSLP receptor, Cytokine receptor-like 2