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Amcinonide
go.drugbank.com/drugs/DB00288ApprovedAmcinonide is a corticosteroid.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigationalMany contain a blackbox warning stating that CNS stimulants, including methylphenidate-containing products and amphetamines, have a high potential for abuse and dependence. … More recently, positron emission tomography (PET) imaging studies in rhesus monkeys have shown that atomoxetine also binds to the serotonin transporter (SERT),[A178111] and blocks the N-methyl-d-aspartate
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: STRATTERA® 80 MG, ATTENTHO®25 MG CAPSULASChlorambucil
go.drugbank.com/drugs/DB00291ApprovedInvestigationalA nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. … Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Synonyms: N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid, N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acidProducts: ลูเคอแรน (เม็ด 2 มก.), Leukeran 2 mg - FilmtablettenPenciclovir
go.drugbank.com/drugs/DB00299ApprovedDisplaying low toxicity and good selectivity, penciclovir is a nucleoside analogue. … Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections.
Synonyms: 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine, 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanineCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingTenofovir disoproxil
go.drugbank.com/drugs/DB00300ApprovedInvestigationalTenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name _Viread_, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase … This drug is prescribed in combination with other drugs for the management of HIV infection as well as for Hepatitis B therapy. Tenofovir disoproxil was initially approved in 2001 [FDA label].
Mixtures: TENARTA®L, TOLAK® E 300/200Categories: P-glycoprotein inhibitors, P-glycoprotein substratesErtapenem
go.drugbank.com/drugs/DB00303ApprovedInvestigationalErtapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics.[L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to treat various bacterial infections.
Synonyms: (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid, (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acidCategories: Heterocyclic Compounds, 2-RingHexafluronium
go.drugbank.com/drugs/DB00941ApprovedHexafluronium bromide is a neuromuscular blocking agent used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium during surgery.
Synonyms: Hexamethylenebis(fluoren-9-yldimethylammonium)Acetylsalicylic acid
go.drugbank.com/drugs/DB00945ApprovedInvestigationalVet approvedAlso known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. … Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].
Synonyms: 2-Acetoxybenzoic acid, o-acetoxybenzoic acidMixtures: Fiorinal-C 1/4, Fiorinal-C 1/2Phenprocoumon
go.drugbank.com/drugs/DB00946ApprovedInvestigationalWithdrawnCoumarin derivative that acts as a long-acting oral anticoagulant.
Synonyms: 4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one, 3-(1-Phenylpropyl)-4-hydroxycoumarinCategories: 4-Hydroxycoumarins, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexFulvestrant
go.drugbank.com/drugs/DB00947ApprovedInvestigationalFulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. … While it is used as monotherapy for the treatment of breast cancers, it is also used in combination with [alpelisib] for the treatment of HR-positive, human epidermal growth factor receptor 2 (HER2)-negative
Synonyms: (7α,17β)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates