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Displaying results 6671 - 6680 of 10000 in total
  1. Drug

    3'-phospho-5'-adenylyl sulfate

    go.drugbank.com/drugs/DB02902
    Experimental

    3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate … This compound also is an important step in the process of sulfur fixation in plants and microorganisms.

  2. Drug

    Hepatitis A Vaccine

    go.drugbank.com/drugs/DB10989
    ApprovedInvestigational

    Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms that include anorexia, nausea, vomiting, and liver failure. Known by several trade names, such as Havrix and Twinrix, the Hepatitis A va...

  3. Drug

    Isoquinoline, 7-(2-(3,6-dihydro-4-(3-(trifluoromethyl)phenyl)-1(2h)-pyridinyl)ethyl)-

    go.drugbank.com/drugs/DB16204
    Investigational

    the Reduction of Inflammation in Patients With Active Rheumatoid Arthritis). … Isoquinoline, 7-(2-(3,6-dihydro-4-(3-(trifluoromethyl)phenyl)-1(2h)-pyridinyl)ethyl)- is under investigation in clinical trial NCT00545454 (Activity and Safety of Oral Administration of SSR150106XB for

  4. Drug

    5'-Guanosine-Diphosphate-Monothiophosphate

    go.drugbank.com/drugs/DB01864
    Experimental

    A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific

    Synonyms: Guanosine 5'-O-(3-thiotriphosphate)
  5. Drug

    Alpibectir

    go.drugbank.com/drugs/DB21561
    Investigational

    Alpibectir has a monoisotopic molecular weight of 332.1 Da. … Alpibectir is under investigation in clinical trial NCT06748937 (A Study of the Early Effects, Safety, and Acceptability of Oral Alpibectir in Combination With Ethionamide).

  6. Drug

    Deoxyribonuclease I

    go.drugbank.com/drugs/DB16523
    Investigational

    Because of the hypothesis that increased concentrations of high-molecular-weight DNA is a factor for airway obstruction, abnormal viscoelastic properties of the sputum, and recurrent exacerbations of respiratory … Deoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7[A227723]. It is normally found in saliva, urine, pancreatic secretions, and blood[A227723].

  7. Drug

    BacTRL-spike

    go.drugbank.com/drugs/DB15811
    Investigational

    As of June, 2020, the company is pursuing a Phase 1, Randomized, Observer-Blind, Placebo-Controlled Trial (NCT04334980) to test the safety and immunogenicity of the vaccine. … BacTRL-Spike is composed of a bacterial medium with colony-forming-units of live Bifidobacterium longum engineered to deliver synthetic DNA encoding spike protein from SARS-CoV-2 contained by plasmids.

  8. Drug

    Amredobresib

    go.drugbank.com/drugs/DB21566
    Investigational

    The usage of the INN stem '-bresib' in the name indicates that Amredobresib is a inhibitor of the bromodomain and extra-terminal motif (BET) family of bromodomain (BRD) protein, antineoplastic. … Amredobresib has a monoisotopic molecular weight of 467.25 Da.

  9. Drug

    Frespaciguat

    go.drugbank.com/drugs/DB21683
    Investigational

    Frespaciguat has a monoisotopic molecular weight of 608.14 Da. … Frespaciguat is under investigation in clinical trial NCT05612035 (Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With

  10. Drug

    Inodiftagene vixteplasmid

    go.drugbank.com/drugs/DB16017
    Investigational

    Inodiftagene vixteplasmid is a plasmid DNA vector encoding the diphtheria toxin A (dT-a) gene under transcriptional regulation of the promoter region of the human H19 gene (an imprinted maternally expressed

    Synonyms: Dna Plasmid Expressing Diphtheria Toxin Triggered By The Presence Of Oncofetal Gene H19