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Abiraterone
go.drugbank.com/drugs/DB05812ApprovedInvestigational[L54773,L54768] As abiraterone has poor oral bioavailability and is susceptible to hydrolysis by esterases, abiraterone acetate was developed as an orally bioavailable prodrug with enhanced stability … Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis
Categories: niraparib and abiraterone, abiraterone and corticosteroidsProducts: XBIRA® 500MG, ZYTIGA FILM-COATED TABLET 500MGAcitretin
go.drugbank.com/drugs/DB00459ApprovedInvestigationalAn oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Categories: Skin and Mucous Membrane AgentsProducts: NOVATRETIN CAPSULE 10MG, Novatretin 10mg CapsulesMidodrine
go.drugbank.com/drugs/DB00211ApprovedInvestigationalAn ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Synonyms: (±)-2-amino-N-(β-hydroxy-2,5-dimethoxyphenethyl)acetamide, 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamideCategories: Adrenergic and Dopaminergic AgentsTocilizumab
go.drugbank.com/drugs/DB06273ApprovedInvestigational[L40164] Subsequently, it was granted approval by Health Canada and the FDA in October [L43697] and December 2022, respectively. … Two biosimilar versions of tocilizumab have since been approved by the FDA: tocilizumab-bavi, in September 2023,[L48385] and Tyenne® (tocilizumab), in June 2024.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: Actemra Concentrate for Solution for Infusion 20mg/ml, ACTEMRA (162 MG SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE)Conjugated estrogens
go.drugbank.com/drugs/DB00286ApprovedInvestigational[T475] The conjugated estrogen mixture was approved for marketing in US in 1942 based on the efficacy against certain conditions. … [T484] The currently approved product of conjugated estrogens was developed by Wyeth Ayerst and FDA approved in 2003.[L5608]
Mixtures: Esterified Estrogens and Methyltestosterone, Esterified Estrogens and MethyltestosteroneCategories: Genito Urinary System and Sex Hormones, conjugated estrogens and bazedoxifeneAvanafil
go.drugbank.com/drugs/DB06237ApprovedIn comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and [vardenafil] but less selectivity than [tadalafil], suggesting a relatively … Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction.
Categories: Drugs Used in Erectile Dysfunction, Genito Urinary System and Sex HormonesSynonyms: (S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamideCefoxitin
go.drugbank.com/drugs/DB01331ApprovedInvestigationalCefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by <i>Streptomyces lactamdurans</i>.
Products: Cefoxitin and Dextrose, Mefoxin Inj 1gm/vial Add-vantagMethocarbamol
go.drugbank.com/drugs/DB00423ApprovedInvestigationalVet approved[Label,L6268] In Canada, methocarbamol can be sold as an over the counter oral medicine at a lower dose that may be combined with [acetaminophen] or [ibuprofen]. … [L6295] A combination product with [acetylsalicylic acid] and [codeine] is available in Canada by prescription.[L6295] Methocarbamol was FDA approved on 16 July 1957.[L6265]
Mixtures: IBUPROFENO + METOCARBAMOL 200MG / 500MG., Acetaminophen 500mg + Methocarbamol 400mg Extra Strength CapletsProducts: Robaxin Inj 100mg/ml, Robaximol Inj 100mg/mlLevocarnitine
go.drugbank.com/drugs/DB00583ApprovedInvestigationalConstituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Categories: Amino Acids and Derivatives, Alimentary Tract and MetabolismSynonyms: 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt