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Pheniramine
go.drugbank.com/drugs/DB01620ApprovedPheniramine is a first-generation antihistamine in the alkylamine class, similar to [brompheniramine] and [chlorpheniramine]. … [A181628] It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs.
Mixtures: Rhume Et De LA Grippe (extra-fort), OCTILIA ALLERGIA E INFIAMMAZIONEPhenylalanine
go.drugbank.com/drugs/DB00120ApprovedInvestigationalNutraceuticalPhenylalanine is an essential aromatic amino acid that is a precursor of melanin, dopamine, noradrenalin (norepinephrine), and thyroxine.
Mixtures: Clinimix E, Clinimix EProline
go.drugbank.com/drugs/DB00172ApprovedInvestigationalNutraceuticalProline is one of the twenty amino acids used in living organisms as the building blocks of proteins. … Proline is sometimes called an imino acid, although the IUPAC definition of an imine requires a carbon-nitrogen double bond.
Mixtures: Clinimix E, Clinimix EIvermectin
go.drugbank.com/drugs/DB00602ApprovedInvestigationalVet approvedWith the advent of 2020 and the COVID-19 pandemic, ivermectin began garnering notoriety due to its off-label use for the prophylaxis and treatment of COVID-19. … Due to a number of factors - for example, the relatively low number of patients per trial and the speed at which these trials were conducted - studies on the use of ivermectin in COVID-19 have been fraught
Mixtures: Heartgard Plus Chewable Tablet for Dogs - Up to 25 lbsFerric pyrophosphate
go.drugbank.com/drugs/DB09147ApprovedInvestigationalThe ferric ion is strongly complexed by pyrophosphate.[A31979] It presents an increasing interest as this insoluble form can be milder in the gastrointestinal tract and present higher bioavailability. … Free iron presents several side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of interactions of iron in plasma.
Mixtures: Timosome FeLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigationalLoperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea.[L42785] The drug was first synthesized in 1969 and used medically in 1976. … [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss.
Mixtures: Meds on the Go, Doc in the Box All Day SupplyProducts: LOPEDIUM T AKUT B AK DURCHOxymorphone
go.drugbank.com/drugs/DB01192ApprovedVet approvedOn June 8, 2017, FDA requested Endo Pharmaceuticals to remove the medication from the market due to opioid misuse and abuse risks associated with the product's injectable reformulation. … It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092).
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeNalbuphine
go.drugbank.com/drugs/DB00844ApprovedInvestigationalNalbuphine is the only opioid analgesic that is not a controlled substance in the United States. … It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeTrimethoprim
go.drugbank.com/drugs/DB00440ApprovedInvestigationalVet approved[L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of … [L11893,L11830] It is structurally and chemically related to [pyrimethamine], another antifolate antimicrobial used in the treatment of plasmodial infections.[T707]
Mixtures: TS-BAC, TS-BACMethocarbamol
go.drugbank.com/drugs/DB00423ApprovedInvestigationalVet approved[A178450] Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of discomforts … [Label,L6268] In Canada, methocarbamol can be sold as an over the counter oral medicine at a lower dose that may be combined with [acetaminophen] or [ibuprofen].
Mixtures: Douleurs Musculaires Et Les Courbatures Extra Fort/muscle and Back Pain Relief Extra Strength