Ferric pyrophosphate is an iron replacement product. Free iron presents several side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of interactions... It presents an increasing interest as this insoluble form can be milder in the gastrointestinal tract and present higher bioavailability.
- Mechanism
- Curator reviewed · 1 reference
The usage of ferric pyrophosphate is based on the strong complex formation between these two species. Besides, the capacity of pyrophosphate to trigger iron removal from transferrin, enhance iron transfer from transferrin to ferritin and promote iron exchange between transferrin molecules. These properties make it a very suitable compound for parenteral administration, iron delivery into circulation and incorporation into hemoglobin.
- Primary indication
- Ferric pyrophosphate is intended to be indicated for the treatment of iron loss or iron deficiency as a formulation with a milder gastrointestinal effect.Curator reviewed · 2 structured indications
- Formula / weight
- Fe4O21P6 · 745.21 g/mol (avg)
- Also known as
- Iron pyrophosphate · Iron(III) pyrophosphate
Resolves to
CADNYOZXMIKYPR-UHFFFAOYSA-BSMILES[Fe+3].[Fe+3].[Fe+3].[Fe+3].[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=OWhat you can answer from here — as of May 11, 2026
Which drugs share a target with Ferric pyrophosphate, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account