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Displaying results 6721 - 6730 of 10000 in total
  1. Drug

    APL-9

    go.drugbank.com/drugs/DB16460
    Investigational

    APL-9 is an investigational drug intended to centrally control the complement cascade at C3, potentially treating various diseases caused by excessive or uncontrolled complement activation. … APL-9 is designed for intravenous administration for acute use

  2. Drug

    1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline

    go.drugbank.com/drugs/DB08555
    Experimental

    This medication is known to target mitogen-activated protein kinase 10. … 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline is a solid. This compound belongs to the isoquinolines and derivatives.

  3. Drug

    Resiquimod

    go.drugbank.com/drugs/DB06530
    Investigational

    It is also being studied to find out if adding it to a tumor vaccine improves the antitumor immune response. It is a type of imidazoquinoline and a type of immunomodulator. … A substance being studied in the treatment of some types of skin cancer. When put on the skin, resiquimod causes some immune cells to make certain chemicals that may help them kill tumor cells.

    Categories: Toll-Like Receptor Agonists
  4. Drug

    Acrizanib

    go.drugbank.com/drugs/DB16081
    Investigational

    Acrizanib is under investigation in clinical trial NCT02355028 (LHA510 Proof-of-concept Study as a Maintenance Therapy for Patients With Wet Age-related Macular Degeneration).

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Teglarinad chloride

    go.drugbank.com/drugs/DB05217
    Investigational

    In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. … GMX1777 is a water-soluble prodrug of the cyanoguanidine compound GMX1778 with potential antineoplastic activity.

  6. Drug

    VPM1002

    go.drugbank.com/drugs/DB15801
    Investigational

    Because Hly is only active at an acidic pH, similar to listeriolysin O, the deletion of urease C was also beneficial for Hly to have optimal bioactivity in the phagosome. … By reducing urease C, phagosome acidification can occur, promoting phagolysosome fusion while also providing the optimal low pH for listeriolysin O stability.

  7. Drug

    Sulfametopyrazine

    go.drugbank.com/drugs/DB00664
    ApprovedWithdrawn

    Long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria.

  8. Drug

    Azvudine

    go.drugbank.com/drugs/DB16407
    Investigational

    Azvudine is under investigation in clinical trial NCT04668235 (Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (Sars-cov-2 Infected)).

  9. Drug

    Chlorotrianisene

    go.drugbank.com/drugs/DB00269
    ApprovedWithdrawn

    A powerful synthetic, non-steroidal estrogen. [PubChem]

  10. Drug

    Emoxypine

    go.drugbank.com/drugs/DB19172
    Investigational

    Emoxypine is under investigation in clinical trial NCT06221826 (MEXIDOL® in the Rehabilitation Treatment of Patients With Acute Cerebral Failure).

    Categories: Compounds used in a research, industrial, or household setting