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Displaying results 6731 - 6740 of 10000 in total
  1. Target

    Stathmin-4

    go.drugbank.com/bio_entities/BE0004003
    TargetHumans

    Exhibits microtubule-destabilizing activity

    Polypeptides: Stathmin-4
  2. Target

    Reticulon-4

    go.drugbank.com/bio_entities/BE0010844
    TargetHumans

    Required to induce the formation and stabilization of endoplasmic reticulum (ER) tubules (PubMed:24262037, PubMed:25612671, PubMed:27619977). They regulate membrane morphogenesis in the ER by promoting tubular ER production (PubMed:24262...

    Polypeptides: Reticulon-4
  3. Target

    Mucin-4

    go.drugbank.com/bio_entities/BE0018599
    TargetHumans

    Membrane-bound mucin, a family of highly glycosylated proteins that constitute the major component of the mucus, the slimy and viscous secretion covering epithelial surfaces (PubMed:10880978). These glycoproteins play important roles in ...

    Polypeptides: Mucin-4Synonyms: MUC-4
  4. Drug

    Brotizolam

    go.drugbank.com/drugs/DB09017
    ApprovedWithdrawn

    Brotizolam is indicated for 2-4 weeks of treatment for severe or debilitating insomnia. … Brotizolam is a sedative-hypnotic thienodiazepine drug which is a benzodiazepine analog. It demonstrates anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant effects.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingInternational brands: Brotizolam M
  5. Drug

    Taniraleucel

    go.drugbank.com/drugs/DB18311
    Investigational

    Synonyms: The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell
  6. Drug

    Dacomitinib

    go.drugbank.com/drugs/DB11963
    ApprovedInvestigational

    Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible … [A40009] Dacomitinib was developed by Pfizer Inc and approved by the FDA on September 27, 2018.

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexProducts: VİZİMPRO 45 MG FİLM KAPLI TABLET, 30 ADET, Vizimpro 45 mg Film-Coated Tablets
  7. Drug

    Epoprostenol

    go.drugbank.com/drugs/DB01240
    ApprovedInvestigational

    A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue.

    Categories: Prostaglandins ISynonyms: Prostaglandin X, (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid
  8. Drug

    Retlirafusp alfa

    go.drugbank.com/drugs/DB17517
    Investigational

    Synonyms: protein with peptide linker ((ggggs)4g) fusion protein with 20-136-type II transforming growth factor .beta. receptor (human isoform 1), disulfide with (85-glutamic acid) human-mus musculus monoclonal, Immunoglobulin G4 (52-glycine, 57-phenylalanine, 227-proline, 233-alanine, 234-alanine, 446-alanine), anti-(human programmed death-ligand 1) (human-mus musculus monoclonal SHR-1316 .gamma.4-chain) fusion
  9. Target

    Eukaryotic translation initiation factor 2 subunit 3

    go.drugbank.com/bio_entities/BE0004636
    TargetHumans

    Member of the eIF2 complex that functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (PubMed:31836389). This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form...

    Polypeptides: Eukaryotic translation initiation factor 2 subunit 3Synonyms: Eukaryotic translation initiation factor 2 subunit gamma X
  10. Drug

    Sulthiame

    go.drugbank.com/drugs/DB08329
    Approved

    Categories: Heterocyclic Compounds, 1-RingProducts: Ospolot 200 mg Filmtabletten, Ospolot 50 mg Filmtabletten