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Displaying results 6741 - 6750 of 10000 in total
  1. Drug

    Reglitazar

    go.drugbank.com/drugs/DB04971
    Experimental

    Reglitazar, an isoxazolidine-3,5-dione derivative, is being developed by Pfizer for the treatment of diabetes. It is the first non-thiazolidenedione to enter clinical trials.

  2. Drug

    IRX-5183

    go.drugbank.com/drugs/DB05653
    Investigational

  3. Drug

    Canis lupus familiaris skin

    go.drugbank.com/drugs/DB10409
    Approved

    Canis lupus familiaris skin allergenic extract is used in allergenic testing.

  4. Drug

    Cedar oil

    go.drugbank.com/drugs/DB10917
    Approved

    Cedar oil (Juniperus virginiana) allergenic extract is used in allergenic testing.

  5. Drug

    Protriptyline

    go.drugbank.com/drugs/DB00344
    Approved

    In depressed individuals, protriptyline exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. … They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation.

    Synonyms: 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine, N-methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine
  6. Drug

    Vadimezan

    go.drugbank.com/drugs/DB06235
    Investigational

  7. Drug

    Perindoprilat

    go.drugbank.com/drugs/DB14213
    Experimental

    The active metabolite of the prodrug Perindopril.

    Categories: Agents Acting on the Renin-Angiotensin System
  8. Drug

    NKG2D-ACE2 CAR-NK Cell

    go.drugbank.com/drugs/DB15727
    Investigational

    The ACE2 is a receptor for SARS-Cov-2, binding to the S-protein of the viral envelope and competitively inhibiting SARS-Cov-2 infection of type II alveolar epithelial cells. … The IL-15 superagonist increases the activity of NK cells and improves their target cytotoxicity. The GM-CSF acts as a neutralizer for the CAR-T cell-mediated cytokine release and neurotoxicity.

  9. Drug

    Tocofibrate

    go.drugbank.com/drugs/DB19752
    Experimental

    Tocofibrate has a monoisotopic molecular weight of 626.41 Da. … The usage of the INN stem '-fibrate' in the name indicates that Tocofibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist.

  10. Drug

    Nicofibrate

    go.drugbank.com/drugs/DB19916
    Experimental

    Nicofibrate has a monoisotopic molecular weight of 305.08 Da. … The usage of the INN stem '-fibrate' in the name indicates that Nicofibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist.