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Guselkumab
go.drugbank.com/drugs/DB11834ApprovedInvestigationalGuselkumab is a human immunoglobulin G1 lambda (IgG1λ) monoclonal antibody that selectively blocks interleukin-23. … IL-23 is an inflammatory cytokine that activates the CD4+ T-helper (Th17) cell pathway to mediate the inflammatory cascade that induces psoriatic plaque formation [A20357].
Products: TREMFYA 100 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET, TREMFYA 100 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADETNabumetone
go.drugbank.com/drugs/DB00461Approved[A179077] While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone still produces significant adverse effects in the GI tract. … Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: NABUFEX 500 MG FILM TABLET, 10 ADET, Nabumetone 750 mgPoractant alfa
go.drugbank.com/drugs/DB09113ApprovedInvestigationalPoractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. … It is used to treat Respiratory Distress Syndrome (RDS) in premature infants with an endogenous pulmonary surfactant deficiency.
Products: CUROSURF 120 MG/1,5 ML INTRATRAKEAL SUSPANSIYON IÇEREN FLAKON, 1 ADET, Curosurf 120 mg - Suspension zur endotracheopulmonalen InstillationGadoteric acid
go.drugbank.com/drugs/DB09132ApprovedInvestigationaldue to a decreased tendency of gadolinium dechelation. … [A263136] Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability, partly due to its macrocyclic structure, and thus has a more favorable safety profile
Categories: Compounds used in a research, industrial, or household settingProducts: CLARİSCAN 0.5 MMOL/ML ENJEKSİYONLUK ÇÖZELTİ, 15 ML, DOTAREM 0,5 MMOL/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 15 MLBethanechol
go.drugbank.com/drugs/DB01019ApprovedBethanechol is a synthetic ester that was initially synthesized in 1935. … [A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous
Products: Myocholine - Glenwood Tabletten 10 mg, Myocholine - Glenwood Tabletten 25 mgPapain
go.drugbank.com/drugs/DB11193ApprovedWithdrawnPapain is also used as an ingredient in various enzymatic debriding preparations. … Papain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme that is found in species of papaya, _Carica papaya_ and _Vasconcellea cundinamarcensis_.
Products: Papaya Enzyme - Tablet 30 mg, NORIPAPAIN 150 000 USP UNITS TABLETInsulin lispro
go.drugbank.com/drugs/DB00046ApprovedInvestigationalMarketed as the brand name product Humalog, insulin lispro begins to exert its effects within 15 minutes of subcutaneous administration, while peak levels occur 30 to 90 minutes after administration. … Due to its duration of action of around 5 hours, Humalog is considered "bolus insulin" as it provides high levels of insulin in a short period of time to mimic the release of endogenous insulin from the
Mixtures: HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/ml, HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/mlCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersGlycine
go.drugbank.com/drugs/DB00145ApprovedInvestigationalNutraceuticalVet approvedA non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Mixtures: TRAVASOL PLUS 15% LIBRE DE BISULFITO, TRAVASOL PLUS 15% LIBRE DE BISULFITOProducts: GLICINA 1.5% SOLUCION DE IRRIGACION, GLICINA IRRIGACION AL 1.5%MASTER MEDICALAnastrozole
go.drugbank.com/drugs/DB01217ApprovedInvestigational[A186865] Aromatase inhibitors, including anastrozole, have become endocrine drugs of choice in the treatment of postmenopausal breast cancer due to a more favourable efficacy and adverse effect profile … as compared to earlier estrogen receptor modulators such as [tamoxifen].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrileOxytetracycline
go.drugbank.com/drugs/DB00595ApprovedInvestigationalVet approvedA tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Mixtures: HEKSA 30 MG/G + 10000 I.U./G MERHEM, POLIMISIN GÖZ MERHEMI, 3,5 GProducts: TERRAFUNGIN 100 MG/2 ML AMPUL, 1 ADET, TERRAFUNGIN 100 MG/2 ML AMPUL, 3 ADET