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Theophylline
go.drugbank.com/drugs/DB00277ApprovedInvestigationalMechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. … A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities.
International brands: Theodur GMixtures: TUSBRON-A JARABE, I D M Expectorant TabRepotrectinib
go.drugbank.com/drugs/DB16826ApprovedInvestigationalRepotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the … [A262056] Repotrectinib possesses a compact macrocyclic structure that both limits adverse interactions with resistance mutation hotspots and targets mutations in the solvent-front region.
Synonyms: (3R,6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN-9-ONE, (7S,13R)-11-Fluoro-7,13-Dimethyl-6,7,13,14-Tetrahydro-1,15-Ethenopyrazolo[4,3-F][1,4,8,10]Benzoxatriazacyclotridecin-4(5H)-OneCategories: MATE 2 Inhibitors, P-glycoprotein inhibitorsGanaplacide
go.drugbank.com/drugs/DB16173InvestigationalGanaplacide is under investigation in clinical trial NCT03167242 (Efficacy and Safety of KAF156 in Combination With LUM-SDF in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria).
Synonyms: 2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanoneCategories: Heterocyclic Compounds, 1-RingTechnetium Tc-99m mebrofenin
go.drugbank.com/drugs/DB09137ApprovedWithdrawnTechnetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. … This is possible as Technetium-99m decays by isomeric transition to technetium-99 through the release of a gamma ray.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Bis(2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetate) technetiumGinseng
go.drugbank.com/drugs/DB01404ApprovedInvestigationalNutraceuticalGinseng is promoted as an adaptogen (a product that increases the body's resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and antioxidant properties
Mixtures: GINSENG-E CAPSULE, BEDOYECTA + GProducts: SOMA Hyulgihwan, SOMA Pet-circleSynthetic camphor
go.drugbank.com/drugs/DB14156ApprovedSynonyms: DL-camphor, 2-bornanoneMixtures: La Vaquita, La Vaquita Extra StrengthAVR-RD-04
go.drugbank.com/drugs/DB18644ExperimentalIt consists of autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin. … AVR-RD-04 is an investigational gene therapy for cystinosis.
Synonyms: autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosinAntineoplaston A10
go.drugbank.com/drugs/DB11702InvestigationalAntineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.
Synonyms: Antineoplaston A 10, BENZENEACETAMIDE, N-(2,6-DIOXO-3-PIPERIDINYL)-, (S)-Categories: Heterocyclic Compounds, 1-Ring(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE
go.drugbank.com/drugs/DB07072ExperimentalSynonyms: (1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINECombretastatin A4
go.drugbank.com/drugs/DB14680ExperimentalSynonyms: Combretastatin A-4, 2'-deoxycombretastatin A1