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Anethole
go.drugbank.com/drugs/DB15916ApprovedWithdrawnCategories: Diet, Food, and Nutrition, Compounds used in a research, industrial, or household settingZeranol
go.drugbank.com/drugs/DB11478ExperimentalVet approvedIt is 3-4x more potent as an estrogen agonist than the related compound zearalenone. … Zeranol is a non-steroidal estrogen agonist. It is a mycotoxin, derived from fungi in the Fusarium family, and may be found as a contaminant in fungus-infected crops.
Categories: Hormones, Hormone Substitutes, and Hormone AntagonistsMesmulogene ancovacivec
go.drugbank.com/drugs/DB06584Investigationalresulting in tumor cell lysis. … A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities
Categories: Amino Acids, Peptides, and ProteinsIsaralgagene civaparvovec
go.drugbank.com/drugs/DB16808InvestigationalIt is developed by Sangamo Therapeutics and investigated in Fabry Disease. … Isaralgagene civaparvovec, formerly known as ST-920, is liver-tropic rAAV 2/6 vector carrying the cDNA for human alpha-galactosidase A (α-Gal A) enzyme.
Zea mays pollen
go.drugbank.com/drugs/DB10357ApprovedZea mays pollen is the pollen of the Zea mays plant. Zea mays pollen is mainly used in allergenic testing.
Mixtures: Mixture of Twenty-Two Standardized and Non-Standardized GrassesADU-S100
go.drugbank.com/drugs/DB14722InvestigationalADU-S100 (MIW815) is a synthetic cyclic dinucleotide (CDN) agonist (activator) of Stimulator of Interferon Genes (STING), a receptor crucial to activate the innate (endogenous) immune system. … ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression of cytokines and chemokines, leading to a robust and durable antigen-specific T-cell mediated immune
Categories: Nucleic Acids, Nucleotides, and NucleosidesAmcipatricin
go.drugbank.com/drugs/DB12333InvestigationalAmcipatricin (as amcipatricin diascorbate; SPK-843) is a water-soluble partricin derivative patented by SPA Societa Prodotti Antibiotici S.p.A. and developed by Aparts and Kaken for the potential treatment … In preclinical models, SPK-843 shows in vitro inhibitory activity comparable to or better than that of Amphotericin B against Candida spp., Cryptococcus neoformans, and Aspergillus spp.
Zotiraciclib
go.drugbank.com/drugs/DB16656InvestigationalVersus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma). … Zotiraciclib is under investigation in clinical trial NCT02942264 (Zotiraciclib (TG02) Plus Dose-dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide
Nurulimab
go.drugbank.com/drugs/DB18946InvestigationalNurulimab is under investigation in clinical trial NCT05732805 (A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-pd-1 Compared to Anti-pd-1 Monotherapy as First-line Treatment in
Categories: prolgolimab and nurulimab, Antineoplastic and Immunomodulating AgentsReproxalap
go.drugbank.com/drugs/DB16688Investigational, and Sjögren-Larsson syndrome. … Reproxalap (previously ADX 102 or NS-2) is a small molecule inhibitor being developed by Aldeyra Therapeutics investigated against dry eye disease, allergic conjunctivitis, noninfectious anterior uveitis
Synonyms: ALD-102