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Ixazomib
go.drugbank.com/drugs/DB09570ApprovedInvestigationalIxazomib is a reversible proteasome inhibitor. Because it is a modified peptide boronic acid with one chiral center,[A264329] it is considered a boronate proteasome inhibitor. … [A264319] It was later approved by Health Canada on August 3, 2016,[L51239] and by the EMA on November 21, 2016.
Synonyms: 2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-5-oxo-1,3,2-dioxaborolane-4,4-diacetic acid, BORONIC ACID, B-((1R)-1-((2-((2,5-DICHLOROBENZOYL)AMINO)ACETYL)AMINO)-3-METHYLBUTYL)-Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexPhenyl salicylate
go.drugbank.com/drugs/DB11071ApprovedPhenyl salicylate is a 2-hydroxybenzoic acid phenyl ester. It is utilized in some manufacturing processes of polymers, lacquers, adhesives, waxes, as well as polishes. … These are polycyclic compounds that is either a polyphenolic compound composed of two or more monocyclic aromatic units linked by an ester bond (depside), or a compound containing the depsidone structure
Mixtures: Urin D/S, Uretron D/SResorcinol
go.drugbank.com/drugs/DB11085ApprovedInvestigationalResorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. … Although it is primarily indicated for use as a topical application, resorcinol also possesses a well-documented anti-thyroidal activity that is generally not relied upon for any kind of formal therapeutic
Synonyms: m-Hydroquinone, m-hydroxyphenolMixtures: HONGOSAN®, Clearskin 2 Tinted Blemish CrmDocusate
go.drugbank.com/drugs/DB11089ApprovedInvestigationalStill docusate is available in over-the-counter products as a common laxative. … Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation[A32201].
Mixtures: Senna-S, Senexon-SProducts: H E B Stool Softener laxative, Doc Q LaceMagnesium citrate
go.drugbank.com/drugs/DB11110ApprovedInvestigationalMagnesium citrate is a low volume and osmotic cathartic agent. … [T215] Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug products under the specifications of oral administration of a maximum concentration of 237 mg.
Mixtures: Q-10 Plus, Formula R TabProducts: BET-R-PREP Magnesium Citrate OralUndecylenic acid
go.drugbank.com/drugs/DB11117ApprovedIt is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones [L1891]. … Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat.
Mixtures: NEOFUNGINA® POLVO, NEOFUNGINA® POLVOProducts: Hongocura M, Hongocura SHypochlorite
go.drugbank.com/drugs/DB11123ApprovedInvestigationalHypochlorite is often used as a chemical reagent for chlorination and oxidation reactions.
Mixtures: K-100, K-100Categories: Compounds used in a research, industrial, or household settingButamben
go.drugbank.com/drugs/DB11148ApprovedWithdrawnButamben is a local anesthetic in the form of n-butyl-p-aminobenzoate. … [A27147] Its structure corresponds to the standard molecule of a hydrophilic and hydrophobic domain separated by an intermediate ester found in most of the local anesthetics.
Trichloroacetate
go.drugbank.com/drugs/DB11152ApprovedInvestigationalTrichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. … In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins, DNA and RNA.
Categories: Compounds used in a research, industrial, or household settingProducts: Trichloroacetic Acid 5%Phenyltoloxamine
go.drugbank.com/drugs/DB11160ApprovedIt is a H1 receptor blocker and a member of the ethanolamine class of antihistaminergic drugs. … Nevertheless, phenyltoloxamine is used to a fairly limited extent in contemporary medicine, with only very few products involving it as an active ingredient.