This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Brand Names
- Tri-chlor
- Generic Name
- Trichloroacetate
- DrugBank Accession Number
- DB11152
- Background
Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins, DNA and RNA. Trichloroacetate is also found in cosmetic treatments and topical formulations as a cauterant, which removes condyloma or warts on the skin.
- Type
- Small Molecule
- Groups
- Approved
- Synonyms
- Not Available
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Therapies
- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Product Ingredients
Ingredient UNII CAS InChI Key Trichloroacetic acid 5V2JDO056X 76-03-9 YNJBWRMUSHSURL-UHFFFAOYSA-N - Brand Name Prescription Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Tri-chlor Liquid .8 g/1g Topical Gordon Laboratories 2010-07-12 Not applicable US 
Trichloroacetic Acid 15% Liquid 15 g/100mL Topical Crc (Cosmoceutical Research Center) 2014-09-24 Not applicable US Trichloroacetic Acid 30% Liquid 30 g/100mL Topical Crc (Cosmoceutical Research Center) 2014-09-24 Not applicable US Trichloroacetic Acid 5% Liquid 5 g/100mL Topical Astral Diagnostics Inc 2020-12-31 Not applicable US Trichloroacetic Acid 50% Liquid 30 g/100mL Topical Crc (Cosmoceutical Research Center) 2014-09-24 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Tri-chlor Trichloroacetic acid (.8 g/1g) Liquid Topical Gordon Laboratories 2010-07-12 Not applicable US Trichloroacetic Acid 15% Trichloroacetic acid (15 g/100mL) Liquid Topical Crc (Cosmoceutical Research Center) 2014-09-24 Not applicable US Trichloroacetic Acid 30% Trichloroacetic acid (30 g/100mL) Liquid Topical Crc (Cosmoceutical Research Center) 2014-09-24 Not applicable US Trichloroacetic Acid 5% Trichloroacetic acid (5 g/100mL) Liquid Topical Astral Diagnostics Inc 2020-12-31 Not applicable US Trichloroacetic Acid 50% Trichloroacetic acid (30 g/100mL) Liquid Topical Crc (Cosmoceutical Research Center) 2014-09-24 Not applicable US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Not Available
- CAS number
- 76-03-9
- InChI Key
- Not Available
- InChI
- Not Available
- IUPAC Name
- Not Available
- SMILES
- Not Available
References
- General References
- Not Available
- External Links
- PubChem Substance
- 347911136
- 618564
- Wikipedia
- Trichloroacetate
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Completed Treatment Keratosis Pilaris (KP) 1 4 Completed Treatment Warts, Genital 1 4 Not Yet Recruiting Treatment Acne Vulgaris 1 4 Recruiting Treatment Benign facial lentigines / Solar Elastosis 1 4 Recruiting Treatment Melasma 1 4 Unknown Status Treatment Melasma 1 3 Completed Treatment Acne Vulgaris 1 2 Unknown Status Treatment Atrophic Varicella Scar 1 Not Available Completed Other Postinflammatory Hyperpigmentation 1 Not Available Completed Treatment Acne Vulgaris 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Solution Topical Liquid Topical .8 g/1g Liquid Topical 15 g/100mL Liquid Topical 30 g/100mL Liquid Topical 5 g/100mL - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
- Not Available
- Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at December 03, 2015 16:51 / Updated at September 28, 2021 21:54