Trichloroacetate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Brand Names
Tri-chlor
Generic Name
Trichloroacetate
DrugBank Accession Number
DB11152
Background

Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins, DNA and RNA. Trichloroacetate is also found in cosmetic treatments and topical formulations as a cauterant, which removes condyloma or warts on the skin.

Type
Small Molecule
Groups
Approved
Synonyms
Not Available

Pharmacology

Indication

Not Available

Pharmacology
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Associated Therapies
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

Products2
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Product Ingredients
IngredientUNIICASInChI Key
Trichloroacetic acid5V2JDO056X76-03-9YNJBWRMUSHSURL-UHFFFAOYSA-N
Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Tri-chlorLiquid.8 g/1gTopicalGordon Laboratories2010-07-12Not applicableUS flag
Trichloroacetic Acid 15%Liquid15 g/100mLTopicalCrc (Cosmoceutical Research Center)2014-09-24Not applicableUS flag
Trichloroacetic Acid 30%Liquid30 g/100mLTopicalCrc (Cosmoceutical Research Center)2014-09-24Not applicableUS flag
Trichloroacetic Acid 5%Liquid5 g/100mLTopicalAstral Diagnostics Inc2020-12-31Not applicableUS flag
Trichloroacetic Acid 50%Liquid30 g/100mLTopicalCrc (Cosmoceutical Research Center)2014-09-24Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Tri-chlorTrichloroacetic acid (.8 g/1g)LiquidTopicalGordon Laboratories2010-07-12Not applicableUS flag
Trichloroacetic Acid 15%Trichloroacetic acid (15 g/100mL)LiquidTopicalCrc (Cosmoceutical Research Center)2014-09-24Not applicableUS flag
Trichloroacetic Acid 30%Trichloroacetic acid (30 g/100mL)LiquidTopicalCrc (Cosmoceutical Research Center)2014-09-24Not applicableUS flag
Trichloroacetic Acid 5%Trichloroacetic acid (5 g/100mL)LiquidTopicalAstral Diagnostics Inc2020-12-31Not applicableUS flag
Trichloroacetic Acid 50%Trichloroacetic acid (30 g/100mL)LiquidTopicalCrc (Cosmoceutical Research Center)2014-09-24Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Not Available
CAS number
76-03-9
InChI Key
Not Available
InChI
Not Available
IUPAC Name
Not Available
SMILES
Not Available

References

General References
Not Available
PubChem Substance
347911136
RxNav
618564
Wikipedia
Trichloroacetate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedTreatmentKeratosis Pilaris (KP)1
4CompletedTreatmentWarts, Genital1
4Not Yet RecruitingTreatmentMelasma1
4RecruitingTreatmentMelasma1
3CompletedTreatmentAcne Vulgaris1
2Unknown StatusTreatmentAtrophic Varicella Scar1
Not AvailableNot Yet RecruitingTreatmentRosacea1
Not AvailableUnknown StatusOtherPostinflammatory Hyperpigmentation1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SolutionTopical
LiquidTopical.8 g/1g
LiquidTopical15 g/100mL
LiquidTopical30 g/100mL
LiquidTopical5 g/100mL
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on December 03, 2015 16:51 / Updated on June 12, 2020 17:42