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Isuzinaxib
go.drugbank.com/drugs/DB19109InvestigationalIsuzinaxib is under investigation in clinical trial NCT05758896 (Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI).
VPM1002
go.drugbank.com/drugs/DB15801InvestigationalThis recombinant BCG, VPM1002, has been created in response and investigated for preventing pulmonary TB in newborns and TB recurrence in adults through post-exposure immunization. … Because Hly is only active at an acidic pH, similar to listeriolysin O, the deletion of urease C was also beneficial for Hly to have optimal bioactivity in the phagosome.
Edaxeterkib
go.drugbank.com/drugs/DB21490InvestigationalEdaxeterkib is under investigation in clinical trial NCT03051035 (First-in-Human Study of KO-947 in Non-Hematological Malignancies). Edaxeterkib has a monoisotopic molecular weight of 469.22 Da. … The usage of the INN stem '-terkib' in the name indicates that Edaxeterkib is a extracellular signal-regulated kinase (ERK) inhibitor.
Ceralasertib
go.drugbank.com/drugs/DB14917InvestigationalCeralasertib is under investigation in clinical trial NCT03682289 (Phase II Trial of AZD6738 Alone and in Combination With Olaparib).
Etokimab
go.drugbank.com/drugs/DB16661InvestigationalEtokimab is under investigation in clinical trial NCT03614923 (Etokimab in Adult Patients With Chronic Rhinosinusitis With Nasal Polyps (Crswnp)).
Zagotenemab
go.drugbank.com/drugs/DB16674InvestigationalZagotenemab is under investigation in clinical trial NCT03518073 (A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease).
Lirentelimab
go.drugbank.com/drugs/DB16728InvestigationalLirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Gefurulimab
go.drugbank.com/drugs/DB18928InvestigationalGefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis).
Epaminurad
go.drugbank.com/drugs/DB18973InvestigationalEpaminurad is under investigation in clinical trial NCT05815901 (A Therapeutic Confirmatory Study of Epaminurad Versus Febuxostat in Gout Patients).
Orismilast
go.drugbank.com/drugs/DB19042InvestigationalOrismilast is under investigation in clinical trial NCT05190419 (Study to Assess the Efficacy and Safety of Orismilast in Psoriasis).