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Paroxetine
go.drugbank.com/drugs/DB00715ApprovedInvestigationalParoxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. … Paroxetine is well tolerated in most patients with a similar adverse effect profile to other members of its drug class.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: (3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine, (−)-(3S,4R)-4-(p-fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidineMethoxamine
go.drugbank.com/drugs/DB00723ApprovedInvestigationalWithdrawnAn alpha-adrenergic agonist that causes prolonged peripheral vasoconstriction. It has little if any direct effect on the central nervous system.
Categories: Adrenergic alpha-1 Receptor AgonistsHomatropine methylbromide
go.drugbank.com/drugs/DB00725ApprovedHomatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics.
Mixtures: Debiline H, BONESPAS® TABLETASSynonyms: 3-alpha-Hydroxy-8-methyl-1-alpha-H,5-alpha-H-tropanium bromide mandelate, 8-Methylhomatropinium bromideNateglinide
go.drugbank.com/drugs/DB00731ApprovedApproximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. … It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPralidoxime
go.drugbank.com/drugs/DB00733ApprovedInvestigationalVet approvedPralidoxime is an antidote to organophosphate pesticides and chemicals. Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. If given within 24 hours,after...
Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-PAMHetacillin
go.drugbank.com/drugs/DB00739ApprovedVet approvedWithdrawnHetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. … Hetacillin has been withdrawn from the market since it has been discovered that it has no therapeutic advantage compared to non-ester derivatives like ampicillin.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6β-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]penicillanic acidHydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approved[A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574] … [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.
Synonyms: Kendall's compound F, Reichstein's substance MInternational brands: Polcort H, Preparation H Hydrocortisone CreamDeferoxamine
go.drugbank.com/drugs/DB00746ApprovedInvestigationalIt forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Deferrioxamine BCarbinoxamine
go.drugbank.com/drugs/DB00748ApprovedCarbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. … This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding.
Mixtures: PHILDEX 2Categories: Heterocyclic Compounds, 1-RingEtodolac
go.drugbank.com/drugs/DB00749ApprovedInvestigationalVet approvedEtodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties.
Mixtures: NuDroxiPAK E-400, ETOTIO 400 MG/8 MG FILM TABLET, 20 ADETCategories: COX-2 Inhibitors, Cytochrome P-450 Substrates