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Displaying results 6871 - 6880 of 10000 in total
  1. Drug

    Brimapitide

    go.drugbank.com/drugs/DB15231
    Investigational

    Brimapitide is under investigation in clinical trial NCT01570205 (Safety, Tolerability and PK of a Single iv Infusion of 10, 40, and 80 µg/kg XG-102 Administered to Healthy Volunteers).

  2. Drug

    Protriptyline

    go.drugbank.com/drugs/DB00344
    Approved

    In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive effect on mood. … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission.

    Synonyms: 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine, 3-(5H-dibenzo[a,d]cyclohepten-5-yl)-N-methyl-1-propanamine
  3. Drug

    Cathinone

    go.drugbank.com/drugs/DB01560
    ExperimentalIllicit

    Internationally, cathinone is categorized as a Schedule I drug. Cathinone was added to the Controlled Substances Act's Schedule I in 1993 in compliance with international laws. … Cathinone is a monoamine alkaloid found in the shrub Catha edulis (Khat).

  4. Drug

    AVR-RD-05

    go.drugbank.com/drugs/DB18631
    Experimental

    It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII). … AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme.

  5. Drug

    Talabostat

    go.drugbank.com/drugs/DB06182
    Investigational

  6. Drug

    Lactobacillus plantarum

    go.drugbank.com/drugs/DB11360
    Investigational

    *Lactobacillus plantarum* is a member of Lactobacillus, or lactic acid bacteria, that it is widely used in the food industry as a microbial starter and probiotic microorganism. … It is considered to be one of versatile species that carry out fermentative and metabolic processes, while exhibiting an antagonistic activity against pathogenic and spoilage microorganisms.

  7. Drug

    Gatralimab

    go.drugbank.com/drugs/DB16528
    Investigational

    Gatralimab is under investigation in clinical trial NCT02389452 (Study of Safety and Efficacy of 6 Ml Synvisc-one (Hylan G-F 20) in Indian Patients With Symptomatic Osteoarthritis of Knee(s) After Initial

  8. Drug

    SB-743921

    go.drugbank.com/drugs/DB05546
    Investigational

  9. Drug

    Retaspimycin

    go.drugbank.com/drugs/DB05626
    Investigational

  10. Drug

    Maropitant

    go.drugbank.com/drugs/DB11427
    ExperimentalVet approved

    It was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use in cats. … Maropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs.