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Displaying results 6881 - 6890 of 10000 in total
  1. Drug

    Lynestrenol

    go.drugbank.com/drugs/DB12474
    ApprovedWithdrawn

    Lynestrenol is a progestin and prodrug of [norethisterone].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ORGAMETRİL 5 MG TABLET, 30 ADET
  2. Indication

    Chronic Kidney Disease, Stage 3 (Moderate)

    go.drugbank.com/conditions/DBCOND0117759
    Drugs: Finerenone
    Synonyms: CKD Stage 3, Chronic Kidney Disease Stage 3
  3. Indication

    Stage 2 HR+/HER2- Breast Cancer

    go.drugbank.com/conditions/DBCOND0169541
    Drugs: Ribociclib
    Synonyms: Stage 2 HR+/HER2- Breast Cancer
  4. Indication

    Stage 3 HR+/HER2- Breast Cancer

    go.drugbank.com/conditions/DBCOND0169542
    Drugs: Ribociclib
    Synonyms: Stage 3 HR+/HER2- Breast Cancer
  5. Indication

    Stage 3 Type 1 Diabetes Mellitus

    go.drugbank.com/conditions/DBCOND0153000
    Drugs: Teplizumab
    Synonyms: Stage 3 Type 1 Diabetes Mellitus
  6. Drug

    Asunaprevir

    go.drugbank.com/drugs/DB11586
    ApprovedWithdrawn

    Asunaprevir, also named BMS-650032, is a potent hepatitis C virus (HCV) NS3 protease inhibitor. … It has been shown to have a very high efficacy in dual-combination regimens with daclatasvir in patients chronically infected with HCV genotype 1b.

    Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitorsProducts: SUNVEPRA® 100MG CÁPSULAS BLANDAS, SUNVEPRA 100 MG KAPSÜL, 56 ADET
  7. Target

    4-trimethylaminobutyraldehyde dehydrogenase

    go.drugbank.com/bio_entities/BE0000287
    TargetHumans

    Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with ...

    Polypeptides: 4-trimethylaminobutyraldehyde dehydrogenaseFunction: 4-trimethylammoniobutyraldehyde dehydrogenase activity
  8. Target

    Dipeptidyl peptidase 4

    go.drugbank.com/bio_entities/BE0000854
    TargetEnzymeHumans

    Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation (PubMed:10900005, PubMed:10951221, PubMed:11772392, PubMed:17287217). Acts as a positive regulator of ...

    Polypeptides: Dipeptidyl peptidase 4Synonyms: ADCP-2, Adenosine deaminase complexing protein 2
  9. Target

    Platelet factor 4

    go.drugbank.com/bio_entities/BE0001129
    TargetHumans

    Neutralizes the anticoagulant effect of heparin by binding more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule.

    Polypeptides: Platelet factor 4Synonyms: PF-4, C-X-C motif chemokine 4
  10. Target

    Sphingomyelin phosphodiesterase 4

    go.drugbank.com/bio_entities/BE0002300
    TargetHumans

    Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide (PubMed:16517606, PubMed:25180167). It has a relevant role in the homeostasis of membrane sphingolipids, thereby influencing membrane integrity, an...

    Polypeptides: Sphingomyelin phosphodiesterase 4Synonyms: nSMase-3, Neutral sphingomyelinase 3