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Glycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers. … [L33110] It is one of the most commonly prescribed anticholinergic medications.
Products: Glycopyrrolate Injection USPPhenobarbital
go.drugbank.com/drugs/DB01174ApprovedInvestigationalIt promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Products: Phenobarbital Sodium Injection, USPColistin
go.drugbank.com/drugs/DB00803ApprovedInvestigationalColistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally. … It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes.
Products: Rican Premix Powder 1,900 IU/mg, Collis Colistin 1,500,000 IU/g Water Soluble PowderTrolamine salicylate
go.drugbank.com/drugs/DB11079ApprovedTrolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. … Trolamine salicylate serves as an active ingredient in topical over-the-counter products for temporary management of mild to moderate muscular and joint pains.
Products: Up and Up Pain Relief Odorless, Up and Up Odor-free Pain Relieving CreamBuspirone
go.drugbank.com/drugs/DB00490ApprovedInvestigationalBelonging to the azaspirodecanedione drug class,[A180991] buspirone is a serotonin 5-HT<sub>1A</sub> receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates … [A180985] First synthesized in 1968 then patented in 1975,[L7375] it is commonly marketed under the brand name Buspar®.
Categories: Dopamine D2 Receptor AntagonistsProducts: Buspirone Hydrochloride Tablets, USPTestosterone undecanoate
go.drugbank.com/drugs/DB13946ApprovedInvestigational[L35970] It was developed via fatty acid esterification of testosterone in order to achieve orally administer testosterone. … Male hypogonadism, resulting from insufficient testosterone secretion, can result symptoms and signs of testosterone deficiency, such as decreased libido, erectile dysfunction, and loss of muscle and bone
Products: NEBIDO 250 MG/ML IM ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET17-beta-hydroxysteroid dehydrogenase type 2
go.drugbank.com/bio_entities/BE0000006TargetEnzymeHumansOxidizes estradiol to estrone, testosterone to androstenedione, and dihydrotestosterone to 5alpha-androstan-3,17-dione. Also has 20-alpha-HSD activity … Catalyzes the NAD-dependent oxidation of the highly active 17beta-hydroxysteroids, such as estradiol (E2), testosterone (T), and dihydrotestosterone (DHT), to their less active forms and thus regulates
Synonyms: Estradiol 17-beta-dehydrogenase 2Azelastine
go.drugbank.com/drugs/DB00972ApprovedInvestigationalAzelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic … [L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first granted FDA approval in 1996.
Products: Azela-Vision sine 0,5 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis, Vividrin Azelastin EDO 0,5 mg/ml Augentropfen, Lösung im EinzeldosisbehältnisAdapalene
go.drugbank.com/drugs/DB00210ApprovedInvestigational[A193521] [Tazarotene] is more efficacious than adapalene but is designated as pregnancy category X and hence is contraindicated in pregnant women. … It is also associated with _Cutibacterium acnes_ (also known as _Propionibacterium acnes_). Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris.
Categories: Retinoids for Topical Use in AcneProducts: Adapalene Gel USP, 0.3%Colchicine
go.drugbank.com/drugs/DB01394ApprovedInvestigationalColchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum autumnale_, or "autumn crocus."[A183611] Its use was first approved by the FDA in 1961. … [L47591] It has also been investigated in other inflammatory and fibrotic conditions.[A183602]
Products: COLSYN (Colchicine Tablets USP 500 mcg)