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Displaying results 681 - 690 of 8412 in total
  1. Target

    Proto-oncogene vav

    go.drugbank.com/bio_entities/BE0010510
    TargetHumans

    Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation

    Polypeptides: Proto-oncogene vavSynonyms: VAV
  2. Target

    Janus (JAK) kinases

    go.drugbank.com/bio_entities/BE0027976
    TargetHumans

    Directly phosphorylates STAT proteins but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors (PubMed:16239216, PubMed:32750333, PubMed:8232552

    Synonyms: JAK-1, JAK-2
  3. Drug

    Nafarelin

    go.drugbank.com/drugs/DB00666
    ApprovedInvestigational

    Nafarelin is a potent synthetic agonist of gonadotropin-releasing hormone with 3-(2-naphthyl)-D-alanine substitution at residue 6.

  4. Drug

    Loratadine

    go.drugbank.com/drugs/DB00455
    ApprovedInvestigational

    Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st genera...

    Mixtures: LORACERT- P JARABE, Wal Itin DCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  5. Drug

    Metoprolol

    go.drugbank.com/drugs/DB00264
    ApprovedInvestigational

    Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. The possibility of the generation of these form...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: DL-metoprolol
  6. Drug

    Undecylenic acid

    go.drugbank.com/drugs/DB11117
    Approved

    Due to its bifunctional properties, undecylenate is also used as a linking molecule to conjugate other biomolecules such as proteins. It serves as an acid moiety for anabolic steroid boldenone. … Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat.

    Products: Dr. Luke Nail Repair Pen, Nu Calmar
  7. Drug

    Sucralose

    go.drugbank.com/drugs/DB15049
    Investigational

    Sucralose is an artificial sweetener used as a sugar substitute.

    Products: DE-LİGHT 6.05 MG TABLET, 100 ADET, DE-LİGHT 6.05 MG TABLET, 300 ADET
  8. Drug

    Methyltestosterone

    go.drugbank.com/drugs/DB06710
    ApprovedInvestigational

    A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methylt...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Tioconazole

    go.drugbank.com/drugs/DB01007
    Approved

    Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. … In addition to being an antifungal, tioconazole also has antibacterial effects on certain Gram-positive cocci bacteria.[L50166]

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP2C19 InhibitorsProducts: Dg Health Tioconazole 1
  10. Drug

    Sodium chlorite

    go.drugbank.com/drugs/DB13210
    Investigational

    Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S. … Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug [A174811, L5413].

    Products: Dr. Guard Special Car Edition, Dr. Guard Special Car Edition Refill Stick