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Displaying results 681 - 690 of 9613 in total
  1. Drug

    Alteplase

    go.drugbank.com/drugs/DB00009
    ApprovedInvestigational

    Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. … [A252345,L43125] It was first approved by the FDA in 1987 for the management of thromboembolic disease, including acute myocardial infarction (AMI).

    Mixtures: Activase RT-PA, Lysatec RT - PaSynonyms: t-PA, rt-PA
  2. Drug

    Aminohippuric acid

    go.drugbank.com/drugs/DB00345
    ApprovedInvestigationalWithdrawn

    Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]

    Synonyms: PAHProducts: Aminohippurate Sodium Pah
  3. Drug

    Raxibacumab

    go.drugbank.com/drugs/DB08902
    ApprovedInvestigational

    Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons.

    Synonyms: PA mAb
  4. Drug

    Carbocisteine

    go.drugbank.com/drugs/DB04339
    ApprovedInvestigational

    Carbocisteine is a mucolytic drug that alleviates respiratory symptoms and infections by reducing the viscosity of mucus, allowing it to be expelled.

    Products: CARBOCISTEINA 50MG/ML, Pabron Kids Cough Syrup 100mg/5ml
  5. Drug

    Tolvaptan

    go.drugbank.com/drugs/DB06212
    ApprovedInvestigational

    Tolvaptan is used to treat low blood sodium levels (hyponatremia) associated with various conditions like congestive heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormones (SIADH). FDA approved on May 19, 2009.

    Products: SAMSCA TABLET 15MG, Samsca Tolvaptan Tablet 15mg
  6. Drug

    Miconazole

    go.drugbank.com/drugs/DB01110
    ApprovedInvestigationalVet approved

    [A214523, L14021] It is currently available as a variety of prescription and over the counter products. … [A203636, A203639] Miconazole was first synthesized in 1969 and first granted FDA approval on January 8, 1974, for sale by INSIGHT Pharmaceuticals as a topical cream.

    Mixtures: Vobaderm 1mg/g + 20mg/g Creme, Monistat 3 Dual-pakProducts: Monazole 7 - Crm 20mg/g, DAKTARIN TINCTURE 20MG/G
  7. Drug

    Anethole trithione

    go.drugbank.com/drugs/DB13853
    Approved

    for many of these aforementioned functions at this time and is only used in limited regions around the world. … treat xerostomia [A27165, A32618, A32620, A32621], to demonstrating an ability to inhibit carcinogenesis by increasing the activity of electrophile detoxification enzymes [A32619], and even being used as

    Products: Sialor Tab 25mg
  8. Drug

    Minocycline

    go.drugbank.com/drugs/DB01017
    ApprovedInvestigational

    Minocycline was first described in the literacture in 1966.[A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. … [A190723] Minocycline was granted FDA approval on 30 June 1971.[L11695]

    Synonyms: (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamideProducts: PMS-minocycline, Enca 100mg
  9. Drug

    Mefenamic acid

    go.drugbank.com/drugs/DB00784
    Approved

    It is an inhibitor of cyclooxygenase.

    Mixtures: MEFA SUSPENSION 50MG/5MLProducts: DYFENAMIC PAEDIATRIC SUSPENSION 50MG/5ML, PMS-mefenamic Acid
  10. Drug

    Clodronic acid

    go.drugbank.com/drugs/DB00720
    ApprovedInvestigationalVet approved

    [A1923] clodronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]

    Products: Ostac Cap 400mg, ACIDO CLODRONICO EG