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Argatroban
go.drugbank.com/drugs/DB00278ApprovedInvestigationalArgatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoi...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Argatra Multidose 100 mg/ml Konzentrat zur Herstellung einer Infusionslösung, ARGAZEM 250 MG/2,5 ML I.V. İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETDicyclomine
go.drugbank.com/drugs/DB00804ApprovedInvestigationalDicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder … [L7982] Dicyclomine was granted FDA approval on 11 May 1950.[L7967]
Mixtures: แอนพัส 520Products: RELESTAL PEDIATRIC SYRUP 10 mg/5 ml, Bentylol Inj 10mg/mlMaraviroc
go.drugbank.com/drugs/DB04835ApprovedInvestigationalIt was originally labelled as UK-427857 during development but was assigned the Maraviroc name as it entered trials. It was approved for use by the FDA in August, 2007.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: CELSENTRI® 150 MG, CELSENTRI 150 MG FILM KAPLI TABLET ,180 ADETMethylprednisolone aceponate
go.drugbank.com/drugs/DB14643ApprovedVet approvedProducts: ECTOPIX M % 0.1 LOSYON, 50 G, ALOCORT M %0.1 EMÜLSİYON, 50 GThimerosal
go.drugbank.com/drugs/DB11590ApprovedDeveloped in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes vaccines. … There has been significant concern regarding its safety and toxicity in the last several decades.
Products: TIMEROSAL TENTUR, 100 ML, TIMEROSAL TENTUR, 1000 MLDecitabine
go.drugbank.com/drugs/DB01262ApprovedInvestigational[A2263, A2264, A2265, A215317, L14962] Decitabine was developed by MGI Pharma/SuperGen Inc. and was approved by the FDA for the treatment of MDS on February 5, 2006. … It was first marketed under the name Dacogen®.[L14962] It is also available as an oral combination product together with the cytidine deaminase inhibitor [cedazuridine].
Synonyms: 5-azadeoxycytidine, 5-aza-2'-deoxycytidineProducts: DECITABINA 50 MG, AURODECINJET 50 MGGriseofulvin
go.drugbank.com/drugs/DB00400ApprovedVet approvedAn antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
International brands: Grison-250Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP3A InducersRosuvastatin
go.drugbank.com/drugs/DB01098ApprovedInvestigational[A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … [A181397, A181403] While all statin medications are considered equally effective from a clinical standpoint, rosuvastatin is considered the most potent; doses of 10 to 40mg rosuvastatin per day were
Synonyms: (3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid, (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acidMixtures: RosuASS 5 mg/100 mg Hartkapseln, RosuASS 10 mg/100 mg HartkapselnNalbuphine
go.drugbank.com/drugs/DB00844ApprovedInvestigationalA narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors.
Products: Nubain 10 mg/ml Injektionslösung, NALBUFINA CLORHIDRATO 10 MG/ML.Simvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigational[A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … [A181397, A181403] While all statin medications are considered equally effective from a clinical standpoint, [rosuvastatin] is considered the most potent; doses of 10 to 40mg [rosuvastatin] per day
Mixtures: SimEz 10 mg/10 mg Tabletten, Ezesim 10 mg/10 mg-TablettenCategories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 Substrates