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Displaying results 6951 - 6960 of 10000 in total
  1. Drug

    Efzofitimod

    go.drugbank.com/drugs/DB16453
    Investigational

    It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.

  2. Drug

    NV1020

    go.drugbank.com/drugs/DB04969
    Investigational

    NV1020, a genetically engineered herpes simplex virus, is a novel anticancer therapeutic.

  3. Drug

    Podofilox

    go.drugbank.com/drugs/DB01179
    Approved

    A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic.

  4. Drug

    Ormeloxifene

    go.drugbank.com/drugs/DB13310
    Experimental

    Ormeloxifene is a third-generation selective estrogen receptor (ER) modulator. … activity in the uterus and breast.

  5. Drug

    Hydrogen fluoride

    go.drugbank.com/drugs/DB11072
    ApprovedInvestigational

    It is used as a chemical reagent in several industrial processes such as oil refinery. It is also used as etchant, cleaning agent, and a reagent to dissolve oxides and silicates.

  6. Drug

    Mericitabine

    go.drugbank.com/drugs/DB12045
    Investigational

    Mericitabine is a prodrug of PSI-6130, which demonstrated excellent potency in preclinical studies. … PSI-6130 is a pyrimidine nucleoside analog inhibitor of HCV RNA polymerase, an enzyme that is necessary for hepatitis C viral replication.

  7. Drug

    Fenbufen

    go.drugbank.com/drugs/DB08981
    Approved

    Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.

  8. Drug

    Amcipatricin

    go.drugbank.com/drugs/DB12333
    Investigational

    In preclinical models, SPK-843 shows in vitro inhibitory activity comparable to or better than that of Amphotericin B against Candida spp., Cryptococcus neoformans, and Aspergillus spp. … SPK-843 exhibits dose-dependent efficacy on murine pulmonary aspergillosis models.

  9. Drug

    Fasedienol

    go.drugbank.com/drugs/DB04968
    Investigational

    PH94B is being developed by Pherin Pharmaceuticals, Inc. for the treatment of social phobias (generalized anxiety disorder). It is a member of a new family of pharmaceutical compounds called vomeropherins.

  10. Drug

    Avotaciclib

    go.drugbank.com/drugs/DB16652
    Investigational

    Avotaciclib is under investigation in clinical trial NCT03579836 (Evaluation of Safety and Efficacy in BEY1107 in Monotherapy Gemcitabine Combination in Patient With Pancreatic Cancer).