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Pemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalPemetrexed was first approved by the FDA in February 4, 2004.[A253907] … Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: Pemetrexed Krka Page 1/1, SUMITREXED®Mebendazole
go.drugbank.com/drugs/DB00643ApprovedInvestigationalVet approvedA benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Synonyms: (5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl esterMixtures: L-OMBRIX-DUET, L-OMBRIX-DUETDextropropoxyphene
go.drugbank.com/drugs/DB00647ApprovedIllicitWithdrawnThe levo-isomer appears to exhibit a very limited antitussive effect.
Synonyms: d-PropoxypheneMixtures: Darvocet-N 50, Darvocet-N 100Leucovorin
go.drugbank.com/drugs/DB00650ApprovedInvestigationalLeucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis. … [L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic
Synonyms: N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid, L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acidCategories: Vitamin B Complex, Heterocyclic Compounds, 2-RingEstrone
go.drugbank.com/drugs/DB00655ApprovedEstrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol.
Synonyms: 3-Hydroxy-1,3,5(10)-estratrien-17-oneCategories: P-glycoprotein inducers, Cytochrome P-450 SubstratesSulfametopyrazine
go.drugbank.com/drugs/DB00664ApprovedWithdrawnLong-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria.
Nilutamide
go.drugbank.com/drugs/DB00665ApprovedInvestigationalNilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors).
Synonyms: 5,5-Dimethyl-3-(α,α,α-trifluoro-4-nitro-m-tolyl)hydantoinCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingPirenzepine
go.drugbank.com/drugs/DB00670ApprovedWithdrawnAn antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duod...
Synonyms: 11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-oneCategories: Heterocyclic Compounds, 2-RingAprepitant
go.drugbank.com/drugs/DB00673ApprovedInvestigationalAprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. … Aprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting
Mixtures: LEMID® 125/80, LEMID® 125/80Categories: Substance P/Neurokinin-1 Receptor Antagonist, Neurokinin 1 AntagonistsGalantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigational[L13571] It is therefore not considered to be a disease-modifying drug. … Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: ANTAMIN ® 8 MG, REMINYL ®ER CAPSULAS DE 8 MG