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Displaying results 61 - 70 of 10000 in total
  1. Drug

    Doxycycline

    go.drugbank.com/drugs/DB00254
    ApprovedInvestigationalVet approved

    Doxycycline is a broad-spectrum antibiotic synthetically derived from [oxytetracycline].[L42880] It is a second-generation tetracycline that was first discovered in 1967. … [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730]

    International brands: Nu-DoxycyclineProducts: Ag-doxycycline, DOXYCYCLIN AL 100
  2. Drug

    Benazepril

    go.drugbank.com/drugs/DB00542
    ApprovedInvestigational

    Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].

    Mixtures: BENAZEPLUS AL 20MG/25MG, BENAZEPLUS AL 10MG/12.5MGProducts: BENAZEPRIL AL 5MG FILMTAB, BENAZEPRIL AL 10MG FILMTAB
  3. Drug

    Selegiline

    go.drugbank.com/drugs/DB01037
    ApprovedInvestigationalVet approved

    A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease.

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Compounds used in a research, industrial, or household settingProducts: SELEGILIN AL 5, SELEGILIN AL 10
  4. Drug

    Atomoxetine

    go.drugbank.com/drugs/DB00289
    ApprovedInvestigational

    is a limiting factor associated with the use of stimulant medications such as [DB00422], [DB01576], and [DB01255]. … Many contain a blackbox warning stating that CNS stimulants, including methylphenidate-containing products and amphetamines, have a high potential for abuse and dependence.

    Products: Ag-atomoxetine, ATOMOXETIN AL 10MG HKP
  5. Drug

    Methylprednisolone aceponate

    go.drugbank.com/drugs/DB14643
    ApprovedVet approved

    Products: Skinatan 1 mg/ml Lösung zur Anwendung auf der Haut, Skinatan 1mg/g Emulsion zur Anwendung auf der Haut
  6. Drug

    Mometasone furoate

    go.drugbank.com/drugs/DB14512
    ApprovedInvestigationalVet approved

    It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906]. … Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295].

    Mixtures: DIRNELID-AZProducts: MOMETASONFUROAT AL 50UG/SP, MOMETASONACREMA AL 0.1 %
  7. Drug

    Gabapentin

    go.drugbank.com/drugs/DB00996
    ApprovedInvestigational

    [A14097,A186179] Gabapentin has some stark advantages as compared with other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and lack of appreciable metabolism … [L8717] It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic pain.

    Products: Ag-gabapentin, GABAPENTIN AL 800MG
  8. Drug

    Phentermine

    go.drugbank.com/drugs/DB00191
    ApprovedIllicitInvestigational

    Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug. … [A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine.

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: ACXION AP, ACXION AP.
  9. Drug

    Doxorubicin

    go.drugbank.com/drugs/DB00997
    ApprovedInvestigational

    Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970. … [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin.

    Categories: BSEP/ABCB11 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: DOXORUBICIN AU 2MG/ML 10MG, DOXORUBICIN AU 2MG/ML 50MG
  10. Drug

    Axicabtagene ciloleucel

    go.drugbank.com/drugs/DB13915
    ApprovedInvestigational

    Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. … The drug has a unique mechanism of action, as it utilizes the patient's own T cells, which play a central role in immune response to cancer.

    Categories: CD19 Receptor Interactions, CD19-directed Chimeric Antigen ReceptorSynonyms: Autologous T cells transduced with retroviral vector encoding an anti-CD-19 CD28/CD3-zeta chimeric antigen receptor