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Chloroprocaine
go.drugbank.com/drugs/DB01161ApprovedInvestigationalBoth can be given as intrathecal injections for peripheral and central nerve block, but only the preservative-free formulation can be used for lumbar and caudal epidural blocks. … Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential.
International brands: Nesacaine-CEProducts: Ampres 10 mg/ml Injektionslösung, Ampres 20 mg/ml InjektionslösungDicloxacillin
go.drugbank.com/drugs/DB00485ApprovedInvestigationalVet approvedOne of the penicillins which is resistant to penicillinase.
Products: CLOXIL 500 MG, BAMAXIN 500 MGNalbuphine
go.drugbank.com/drugs/DB00844ApprovedInvestigationalIt appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors.
Products: Nubain 10 mg/ml Injektionslösung, NALBUFINA CLORHIDRATO 10 MG/ML.Levamisole
go.drugbank.com/drugs/DB00848ApprovedInvestigationalVet approvedWithdrawn[A178117, A178123] Levamisole was withdrawn from the American market in 2000 due to its ability to cause serious adverse effects, including agranulocytosis. … [A178117] It was manufactured by _Janssen_ and first used in 1969 as an agent to treat worm infestations[A178123] Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer.
Products: PARAKS 40 MG TABLET, 1000 ADET, PVP- LEVAMISOLE POUR-ON SOLUTION 20 %w/vNivolumab
go.drugbank.com/drugs/DB09035ApprovedInvestigational[L12129] It is also available in combination with [relatlimab] under the brand name Opdualag.[L41265,L49996,L50001] … [A35203] It was developed by Bristol Myers Squibb.[L12129] Nivolumab was granted FDA approval on 22 December 2014.
Categories: Immunoglobulin G, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsSynonyms: ABP 206Buspirone
go.drugbank.com/drugs/DB00490ApprovedInvestigational[A180985] First synthesized in 1968 then patented in 1975,[L7375] it is commonly marketed under the brand name Buspar®. … It has also been used as a second-line therapy for unipolar depression when the use of selective serotonin reuptake inhibitors (SSRIs) is deemed clinically inadequate or inappropriate.
Products: NOPIRON 10 MG TABLET, 100 ADET, NOPIRON 5 MG TABLET, 100 ADETRopivacaine
go.drugbank.com/drugs/DB00296ApprovedInvestigationalIt exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.[L42140]
Synonyms: L-N-n-propylpipecolic acid-2,6-xylidideProducts: Braun 10 mg/ml Injektionslösung, Naropin 10 mg/ml - InjektionslösungPioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigational[A19757] PPARs are ligand-activated transcription factors that are involved in the expression of more than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis. … [L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert _in vivo_ with little consequence
Mixtures: DROPIA-MET 15/500 MG FILM KAPLI TABLET, 180 ADET, PIOGLITAZONE E METFORMINA EGProducts: PIOGLITAZONE EG, PIO - LN 15Sotalol
go.drugbank.com/drugs/DB00489ApprovedInvestigational[A178579] It was the first of the class III anti arrhythmic drugs.[A178579] Sotalol was first approved as an oral tablet on 30 October 1992.
Products: PMS-sotalol - 240 mg, SOTALEX 160 MGTolevamer
go.drugbank.com/drugs/DB01344ApprovedIt may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. … It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Products: REDUPOT 880 MG GRANÜL, 20 ADET, POTEX 880 MG / 1 G GRANÜL, 20 ADET