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Glycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approvedwell as reducing cardiac inhibitory reflexes;[L33120] and reducing bronchoconstriction in COPD. … [A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers.
Sevasemten
go.drugbank.com/drugs/DB18983InvestigationalSevasemten is under investigation in clinical trial NCT05291091 (Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)).
Cupric sulfate
go.drugbank.com/drugs/DB06778ApprovedSome of its secondary uses are as a raw material in the preparation of other copper compounds, as a reagent in analytic chemistry, as an electrolyte for batteries and electroplating baths, and in medical … This forms as large, bright blue crystals containing five molecules of water (CuSO4∙5H2O) and is also known as _blue vitriol_. The anhydrous salt is created by heating the hydrate to 150 °C (300 °F).
Desflurane
go.drugbank.com/drugs/DB01189ApprovedInvestigationalDesflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as [methoxyflurane], [sevoflurane], [enflurane], or [isoflurane].
Zinc gluconate
go.drugbank.com/drugs/DB11248ApprovedInvestigationalVet approvedIt is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity. … Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA [L2081].
Isoflavone
go.drugbank.com/drugs/DB12007ApprovedInvestigationalWithdrawnIsoflavone is found as one of constituents in oral over-the-counter dietary supplements indicated for improved bone mass density and body fat regulation. … Isoflavone is a soy phytoestrogen and a biologically active component of several agriculturally important legumes such as soy, peanut, green peas, chick peas and alfalfa [A33103].
Tasonermin
go.drugbank.com/drugs/DB11626Approvedof the limbs as the product Beromun. … It was approved for use by the European Medicines Agency in April of 1999 for use as an adjunt to surgery for the subsequent removal of the tumor and in palliative care for irresectable soft tissue sarcoma
Plasma protein fraction (human)
go.drugbank.com/drugs/DB13968ApprovedInvestigationalThe plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma. … [L2262] The proteins in PPFh are stabilized with sodium caprylate and acetyltryptophan and it contains some electrolytes such as sodium, potassium and chloride.[L2261]
Synthetic Conjugated Estrogens, B
go.drugbank.com/drugs/DB09318ApprovedMarketed under the brand name Premarin, CEEs are the most frequently used form of conjugated estrogens. … There is currently no generic form of CEEs available as a detailed analytical characterization of the active ingredients or of their estrogenic activity is not available at this time.
Olipudase alfa
go.drugbank.com/drugs/DB12835ApprovedInvestigational[A251600] Olipudase alfa works to hydrolyze sphingomyelin accumulated in body tissues, such as the lungs, liver, spleen, kidneys, and bone marrow. … [A251590] It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease.