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Itepekimab
go.drugbank.com/drugs/DB16206InvestigationalItepekimab is under investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-il-33 Mab) in Patients With Moderate-to-severe
Categories: Amino Acids, Peptides, and ProteinsApolizumab
go.drugbank.com/drugs/DB06467InvestigationalApolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers.
Categories: Amino Acids, Peptides, and ProteinsNanoparticle Epirubicin
go.drugbank.com/drugs/DB16248InvestigationalNanoparticle Epirubicin is under investigation in clinical trial NCT03168061 (Dose-escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma).
Categories: Amino Acids, Peptides, and ProteinsAtrial natriuretic peptide receptor 1
go.drugbank.com/bio_entities/BE0000556TargetHumansand subsequently PRKAA1, thereby controlling blood pressure and maintaining cardiovascular homeostasis (PubMed:36016499) … Plays an essential role in the regulation of endothelial cell senescence and vascular aging (PubMed:36016499).
Synonyms: ANP-AAtrial natriuretic peptide receptor 2
go.drugbank.com/bio_entities/BE0000997TargetHumansReceptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth
Synonyms: ANP-BVolagidemab
go.drugbank.com/drugs/DB16421InvestigationalVolagidemab is under investigation in clinical trial NCT03117998 (Multiple Dose Study to Evaluate the Efficacy, Safety and Pharmacodynamics of REMD-477 in Subjects With Type 1 Diabetes Mellitus).
Categories: Amino Acids, Peptides, and ProteinsPCI-27483
go.drugbank.com/drugs/DB13000InvestigationalPCI-27483 has been used in trials studying the treatment of Pancreatic Cancer, Ductal Adrenocarcinoma, and Exocrine Pancreatic Cancer.
Categories: Amino Acids, Peptides, and ProteinsMethoxy arachidonyl fluorophosphonate
go.drugbank.com/drugs/DB02465ExperimentalMethoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. … It inhibits phospholipase A2 and fatty acid amide hydrolase with special potency, displaying IC50 values in the low-nanomolar range.
Melengestrol acetate
go.drugbank.com/drugs/DB14659ExperimentalA 6-methyl progesterone acetate with reported glucocorticoid activity and effect on estrus.
Categories: Hormones, Hormone Substitutes, and Hormone AntagonistsAzidocillin
go.drugbank.com/drugs/DB08795ExperimentalAzidocillin is a penicillin antibiotic similir to ampicillin.