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Displaying results 7021 - 7030 of 10000 in total
  1. Drug

    Necitumumab

    go.drugbank.com/drugs/DB09559
    ApprovedInvestigationalWithdrawn

    Necitumumab is approved for use in combination with cisplatin and gemcitabine as a first-line treatment for metastatic squamous non-small cell lung cancer (NSCLC). … It functions by binding to epidermal growth factor receptor (EGFR) and prevents binding of its ligands, a process that is involved in cell proliferation, metastasis, angiogenesis, and malignant progression

  2. Drug

    Ixazomib

    go.drugbank.com/drugs/DB09570
    ApprovedInvestigational

    Ixazomib is a reversible proteasome inhibitor. Because it is a modified peptide boronic acid with one chiral center,[A264329] it is considered a boronate proteasome inhibitor. … [A264319] It was later approved by Health Canada on August 3, 2016,[L51239] and by the EMA on November 21, 2016.

    Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-5-oxo-1,3,2-dioxaborolane-4,4-diacetic acid, BORONIC ACID, B-((1R)-1-((2-((2,5-DICHLOROBENZOYL)AMINO)ACETYL)AMINO)-3-METHYLBUTYL)-
  3. Drug

    Phenyl salicylate

    go.drugbank.com/drugs/DB11071
    Approved

    Phenyl salicylate is a 2-hydroxybenzoic acid phenyl ester. It is utilized in some manufacturing processes of polymers, lacquers, adhesives, waxes, as well as polishes. … These are polycyclic compounds that is either a polyphenolic compound composed of two or more monocyclic aromatic units linked by an ester bond (depside), or a compound containing the depsidone structure

    Mixtures: Urin D/S, Uretron D/S
  4. Drug

    Resorcinol

    go.drugbank.com/drugs/DB11085
    ApprovedInvestigational

    Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. … Although it is primarily indicated for use as a topical application, resorcinol also possesses a well-documented anti-thyroidal activity that is generally not relied upon for any kind of formal therapeutic

    Mixtures: HONGOSAN®, Clearskin 2 Tinted Blemish CrmSynonyms: m-Hydroquinone, m-hydroxyphenol
  5. Drug

    Cocoa butter

    go.drugbank.com/drugs/DB11086
    Approved

    Still, it is a common active ingredient for prevention of skin dryness in cosmetic and skincare products. … It is a rich source of monounsaturated and saturated fatty acids [A33040] that mainly contains approximately 33% [DB04224], 25% [DB03796], and 33% [DB03193] [A20409] but does not contain caffeine or theobromine

    Mixtures: Calmol 4, Preparation HProducts: Coconut Cosmetics 3-in-1 Serum, Suppo-H 1000mg/sup
  6. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    ApprovedInvestigational

    Still docusate is available in over-the-counter products as a common laxative. … Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation[A32201].

    Mixtures: Senna-S, Senexon-SProducts: H E B Stool Softener laxative, Doc Q Lace
  7. Drug

    Plantago seed

    go.drugbank.com/drugs/DB11097
    ApprovedInvestigational

    Regardless, this agent is most predominantly used as a gentle laxative agent in many parts of the world that is more commonly referred as psyllium or psyllium husk.

    Mixtures: Multilax 1 CapProducts: Fibresyl 1 Cap 610mg, Fibre Syl 2 Cap 435mg
  8. Drug

    Magnesium citrate

    go.drugbank.com/drugs/DB11110
    ApprovedInvestigational

    Magnesium citrate is a low volume and osmotic cathartic agent. … [T215] Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug products under the specifications of oral administration of a maximum concentration of 237 mg.

    Mixtures: Q-10 Plus, Formula R TabProducts: BET-R-PREP Magnesium Citrate Oral
  9. Drug

    Undecylenic acid

    go.drugbank.com/drugs/DB11117
    Approved

    It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones [L1891]. … Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat.

    Mixtures: NEOFUNGINA® POLVO, NEOFUNGINA® POLVOProducts: Hongocura M, Hongocura S
  10. Drug

    Hypochlorite

    go.drugbank.com/drugs/DB11123
    ApprovedInvestigational

    Hypochlorite is often used as a chemical reagent for chlorination and oxidation reactions.

    Mixtures: K-100, K-100Categories: Compounds used in a research, industrial, or household setting