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Displaying results 7071 - 7080 of 10000 in total
  1. Drug

    Necuparanib

    go.drugbank.com/drugs/DB16251
    Investigational

    Necuparanib is under investigation in clinical trial NCT01621243 (M402 in Combination With Nab-paclitaxel and Gemcitabine in Pancreatic Cancer).

  2. Drug

    ABX-196

    go.drugbank.com/drugs/DB16339
    Investigational

    ABX-196 is under investigation in clinical trial NCT03897543 (ABX196 in Combination With Nivolumab in Patients With Hepatocellular Carcinoma).

  3. Drug

    HE-2200

    go.drugbank.com/drugs/DB06257
    Experimental

  4. Drug

    Methoxy arachidonyl fluorophosphonate

    go.drugbank.com/drugs/DB02465
    Experimental

    It inhibits phospholipase A2 and fatty acid amide hydrolase with special potency, displaying IC50 values in the low-nanomolar range. … Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases.

  5. Drug

    Masilukast

    go.drugbank.com/drugs/DB16227
    Investigational

    Masilukast is under investigation in clinical trial NCT01740986 (Safety and Efficacy of SA09012 in Asthma).

  6. Drug

    Petesicatib

    go.drugbank.com/drugs/DB15297
    Investigational

    Petesicatib is under investigation in clinical trial NCT02295332 (A Study of RG7625 in Healthy Volunteers).

  7. Drug

    Elraglusib

    go.drugbank.com/drugs/DB16047
    Investigational

    Elraglusib is under investigation in clinical trial NCT04218071 (Actuate 1901: 9-ING-41 in Myelofibrosis).

    Synonyms: 3-(5-Fluoro-benzofuran-3-yl)-4-(5-methyl-5H-(1,3)dioxolo(4,5-F)indol-7-yl)-pyrrole-2,5-dione, 1H-Pyrrole-2,5-dione, 3-(5-fluoro-3-benzofuranyl)-4-(5-methyl-5H-1,3-dioxolo(4,5-F)indol-7-yl)-
  8. Drug

    Olomorasib

    go.drugbank.com/drugs/DB21697
    Investigational

    Olomorasib is a small molecule drug. The usage of the INN stem '-rasib' in the name indicates that Olomorasib is a Ras protein inhibitor. … Olomorasib is under investigation in clinical trial NCT06890598 (Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small

  9. Drug

    Picoplatin

    go.drugbank.com/drugs/DB04874
    Investigational

    Picoplatin is a cytotoxic platinum compound in clinical development for the treatment of patients with solid tumors. … It causes apoptosis (cell death) by binding to DNA and interfering with DNA replication and transcription.

  10. Drug

    SYNB1353

    go.drugbank.com/drugs/DB17666
    Investigational

    It is designed to consume methionine in the gastrointestinal tract to prevent its absorption and conversion into homocysteine.[L45983] … SYNB1353 is a strain of the probiotic bacteria _Escherichia coli_ (_E. coli_) type Nissle and an engineered probiotic drug.