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Budesonide
go.drugbank.com/drugs/DB01222ApprovedInvestigationalBudesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. … [A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598] It is also available in a combination product with [formoterol].[L10619]
Mixtures: Budesonide and Formoterol Fumarate Dihydrate, Budesonide and Formoterol Fumarate DihydrateCategories: Alimentary Tract and Metabolism, salbutamol and budesonideAlfuzosin
go.drugbank.com/drugs/DB00346Approved[A228483] Alfuzosin is an alpha-1 adrenergic blocker used in the symptomatic treatment of BPH that works by relaxing the muscles in the prostate and bladder neck. … [L31593] It was initially approved by the FDA in 2003 and is marketed by several pharmaceutical companies.[L9251]
Categories: Drugs Used in Benign Prostatic Hypertrophy, alfuzosin and finasterideSynonyms: (±)-N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furamide, N-[3-[(4-amino-6,7-dimethoxy-quinazolin-2-yl)- methyl-amino]propyl] tetrahydrofuran- 2-carboxamideMitomycin
go.drugbank.com/drugs/DB00305ApprovedInvestigationalMitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of _Streptomyces caespitosus_. … [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix.
Categories: Compounds used in a research, industrial, or household setting, Indicators and ReagentsProducts: Mutamycin Inj 5mg/vial, Mutamycin Inj 20mg/vialIpilimumab
go.drugbank.com/drugs/DB06186ApprovedInvestigational[L12126] Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes.[A35065,A35080,L12126] Ipilimumab was developed by Bristol-Myers Squibb and Medarex. … Ipilimumab is a fully humanized IgG1 monoclonal antibody that blocks cytotoxic T lymphocyte antigen-4 (CTLA-4).
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: YERVOY 50MG/10ML IV INFUZYONLUK ÇOZELTI KONSANTRESI ICEREN FLAKON, 1 ADET, YERVOY INJECTION CONCENTRATE 5MG/MLNemvaleukin alfa
go.drugbank.com/drugs/DB18187InvestigationalSynonyms: Cys125>Ser51), fused via peptidyl linker (60GG61) to human interleukin 2 fragment (62-132), fused via peptidyl linker (133GSGGGS138) to human interleukin 2 receptor α-chain fragment (139-303), produced in, Fusion protein comprised of a circularly-permuted interleukin-2 (IL-2) with the extracellular domain of IL-2 receptor alphaQuinapril
go.drugbank.com/drugs/DB00881ApprovedInvestigationalQuinapril is the ethyl ester prodrug of the non-sulfhydryl angiotensin converting enzyme inhibitor quinaprilat.[L8420,L8423] It is used to treat hypertension and heart failure. … [L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Mixtures: ACCUZIDE 10MG/12.5MG, QUINAPLUS AL 10MG/12.5MGCategories: ACE Inhibitors and Diuretics, quinapril and diureticsBivalirudin
go.drugbank.com/drugs/DB00006ApprovedInvestigationalBecause it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial thromboplastin time, international normalized ratio and blood pressure. … Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously.
Categories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsProducts: ANGIOMAX® POLVO LIOFILIZADO PARA RECONSTRUIR A SOLUCIÓN INYECTABLE (50MG/ML), Bivalirudin in 0.9% Sodium ChlorideChlorpropamide
go.drugbank.com/drugs/DB00672ApprovedWithdrawnUp to 80% of the single oral dose of chlorpropramide is metabolized, likely in the liver; 80-90% of the dose is excreted in urine as unchanged drug and metabolites. … Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).
Categories: Drugs Used in Diabetes, Alimentary Tract and MetabolismSynonyms: N-(4-chlorophenylsulfonyl)-N'-propylurea, N-(p-chlorobenzenesulfonyl)-N'-propylureaCocoa butter
go.drugbank.com/drugs/DB11086ApprovedCocoa butter is included in chocolate and other food products, and can also be found in over-the-counter skin products such as lotions, creams, and bars intended to maintain skin softness. … It is a rich source of monounsaturated and saturated fatty acids [A33040] that mainly contains approximately 33% [DB04224], 25% [DB03796], and 33% [DB03193] [A20409] but does not contain caffeine or theobromine
Mixtures: Up and Up Hemorrhoidal, Glow And ShineCategories: Diet, Food, and Nutrition, Antipruritics and Local AnestheticsVoriconazole
go.drugbank.com/drugs/DB00582ApprovedInvestigational[A236050] Voriconazole was approved by the FDA under the trade name Vfend on May 24, 2002.[L34660] … These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections.
Categories: Triazole and tetrazole derivatives, Metabolic Side Effects of Drugs and SubstancesProducts: VORICONAZOL ARISTO 100MG, VFEND 50MG TABLET