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Alitretinoin
go.drugbank.com/drugs/DB00523ApprovedAn important regulator of gene expression during growth and development, and in neoplasms. Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess o...
Synonyms: (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acidMixtures: Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05%Risperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigational[L12885] Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors, and carries lesser activity at several off-targets
Categories: Adrenergic alpha-1 Receptor Antagonists, Heterocyclic Compounds, 1-RingInternational brands: Risperidal M-TabCanrenoic acid
go.drugbank.com/drugs/DB09015ApprovedInvestigationalWithdrawnCanrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Products: Aldactone 200 mg/ 10 ml Injektionslösung, POTASSIO CANRENOATO EGBeta-lactamase OXA-10
go.drugbank.com/bio_entities/BE0001274TargetEnzymePseudomonas aeruginosaHydrolyzes both carbenicillin and oxacillin.
Polypeptides: Beta-lactamase OXA-10Amiodarone
go.drugbank.com/drugs/DB01118ApprovedInvestigationalAmiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpat...
Products: AMIODARONA 150 MG/ 3 ML, CORDARONE INJECTION 150 mg/3 mlNortriptyline
go.drugbank.com/drugs/DB00540ApprovedInvestigationalNortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Synonyms: 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamineCategories: Adrenergic alpha-1 Receptor AntagonistsCytosolic 10-formyltetrahydrofolate dehydrogenase
go.drugbank.com/bio_entities/BE0000933TargetHumansCytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide (PubMed:19933275, PubMed:21238436).
Polypeptides: Cytosolic 10-formyltetrahydrofolate dehydrogenaseSynonyms: 10-FTHFDHBone morphogenetic protein 10
go.drugbank.com/bio_entities/BE0010910TargetHumansRequired for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors s...
Polypeptides: Bone morphogenetic protein 10Synonyms: BMP-10Fasted triglycerides >500 mg/dL
go.drugbank.com/conditions/DBCOND0114821Drugs: Fenofibric acidSynonyms: Fasted triglycerides >500 mg/dLAzithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalIn March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine]. … Azithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl
Categories: Experimental Unapproved Treatments for COVID-19Products: AZITHROMYCIN FOR INJECTION 500 MG/VIAL , 10 ML LYO VIAL, AZYDROP®15 MG/G